Plasma Protein Polymorphism in HIV-Seropositive Patients: Gc- and Tf*c-Subtypes and Pi-System
The paper reports on the distribution of three plasma protein systems in serum samples from 99 HIV-seropositive patients: Gc-subtyping, Tfc-subtyping and Pi- (alpha1-antitrypsin) system. In the Gc-system — as in further studies — we found evidence for non-association of Gc-subtypes — especially 1F — with HIV-infection. Also the distribution of Tfc-subtypes seems to be very similar to studies on healthy persons. In the Pi-system this pilot study led to the suspicion that the phenotype Pi*M2 is overrepresented. The distribution found in these patients is not comparable with the control group.
KeywordsHealthy Person Spot Check Relative Protection Codominant Allele Iron Binding Glycoprotein
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- See: Huckenbeck W, Bonte W, Kuntz BME, Brüster HTH (1989) Plasmaprotein-Polymorphismen bei HIV-seropositiven Probanden: GC- und TF*C-Subtypen, PI-, C3- und BF-System Adli Tip Dergesi (in press)Google Scholar