Hospital Experience with Bifonazole/Urea

  • W.-I. Worret
Conference paper


As the treatment of the onychomycoses still presents unsolved difficulties, such as defective penetration of topical antimycotics, immobilization and occasional onychodysplasia after nail removal, and sometimes serious side-effects during systemic therapy, the clinician is always interested in new remedies, especially if these promise a favorable activity/side-effect spectrum and the patient remains fit for work during treatment. The idea of detaching affected nails by means of appropriate chemicals is not new, although this form of treatment has never been properly carried through. Either the keratolyses were too aggressive for the surrounding healthy tissue, or ineffective due to a too low dosage, or pharmaceutically unstable. There were added difficulties with administration, resulting in poor compliance.


Nail Plate Trichophyton Rubrum Mycologic Cure Trichophyton Mentagrophytes Surrounding Healthy Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

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  • W.-I. Worret

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