• O.-E. Lund


Nepomuk Nussbaum discussed in 1853 in his doctoral and in 1856 in his professorial thesis the artificial cornea (“Cornea artificialis”). In experiments on his own skin he had proven that alloplastic material could be tolerated (glass cylinder). Weber (1855) and later Heusser (1860) used such material on the human eye. These experiments on keratoprosthesis were toward the end of the last century (1887) intensively continued by A. von Hippel. Salzer (Munich) reported in 1898 about intracorneal keratoprosthesis made of horn (fixation margin) and quartz (optical cylinder); these were well tolerated for 2 3/4 years [53, 54].


Anterior Chamber Oral Mucosa Synthetic Material Corneal Stroma Corneal Dystrophy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Aquavella JV, Rao NG, Brown AC, Harris JK (1982) Keratoprosthesis, Results, Complications, and Management. Ophthalmol 89: 665–660Google Scholar
  2. 2.
    Barnham JJ, Roper-Hall MJ (1983) Keratoprothesis: a longterm review. Br J Ophthalmol 67: 468–474PubMedCrossRefGoogle Scholar
  3. 3.
    Baron MA (1954) Prothèsis cornéenes et cristalliniennes en matière plastique. (Presentation d’un film). Bull Soc franc Ophtalmol 67: 386–390Google Scholar
  4. 4.
    Barraquer J (1960) Inclusion de protesis opticas corneanes, corneas acrilicas o queratoprotesis. Ann Inst Barraquer 1: 243–247Google Scholar
  5. 5.
    Bedilo VY (1974) Remote results of penetrating prosthesing of leucomas due to severe chemical burns. Oftalmol Zh 29: 403–404Google Scholar
  6. 6.
    Bigar F, Krähenmann A, Landolt E, Witmer R (1978) Die Gewebeverträglichkeit bioaktiver Glaskeramik in der Hornhaut und Bindehaut. Ber Dtsch Ophthalmol Ges 75: 192–196Google Scholar
  7. 7.
    Buxton JN (1977) Symposium: Keratoprothesis. Personal Experiences. Ophthalmol 83: 268–270Google Scholar
  8. 8.
    Cardona H (1962) Keratoprothesis: Acrylic optical cylinder with supporting intralamellar plate. Am J Ophthalmol 54: 284–294PubMedGoogle Scholar
  9. 9.
    Cardona H (1964) Plastic Keratoprothesis: A description of the plastic material and comparative histologic study of recipient corneas. Am J Ophthalmol 58: 247–252PubMedGoogle Scholar
  10. 10.
    Cardona H (1966) Anterior and posterior mushroom keratoprosthesis: An experimental study. Am J Ophthalmol 61: 498–504PubMedGoogle Scholar
  11. 11.
    Cardona H (1969) Mushroom transcorneal keratoprosthesis. Am J Ophthalmol 68: 604–612PubMedGoogle Scholar
  12. 12.
    Cardona H (1976) Prosthokeratoplasty in chemical burns and ocular pemphigoid. Can J Ophthalmol 11: 35–37PubMedGoogle Scholar
  13. 13.
    Cardona H, deVoe AG (1977) Prosthokeratoplasty. Trans Amer Acad Ophthalmol Otolaryngol 83: 271–280Google Scholar
  14. 14.
    Cardona H, Castroviejo R, deVoe AG (1962) The Cardona Keratoprothesis. First Clinical Evaluation. Concilium Ophthalmologicum X IX Vol IIGoogle Scholar
  15. 15.
    Cardona H, Castroviejo R, deVoe AG (1966) Techniques of prosthokeratoplasty: Further evaluation of results with the Cardona Keratoprothesis. Exc Med Internat Congr Series 146: 837–847Google Scholar
  16. 16.
    Castroviejo R, Cardona H, deVoe AG (1969) The present status of prosthokeratoplasty. Trans Amer Ophthalmol Soc 67: 207–234Google Scholar
  17. 17.
    Choyce DP (1968) The present status of intra-cameral and intra-corneal implants. Can J Ophthalmol 3: 295–311PubMedGoogle Scholar
  18. 18.
    Choyce DP (1972) The present status of keratoprosthesis. Israel J Med Sci 8: 1285–1289PubMedGoogle Scholar
  19. 19.
    Choyce DP (1974) The Choyce 2-piece perforating keratoprosthesis. Seventy cases 1967–1973. Trans Ophthalmol Soc UK 93: 333–342Google Scholar
  20. 20.
    de Voe AG (1971) A review of the techniques of keratoprostheses. Sury Ophthalmol 16Google Scholar
  21. 21.
    deVoe AG (1973) Current status of the keratoprosthesis. Trans Ophthal Soc NZ 25: 127–129Google Scholar
  22. 22.
    Dohlman CH, Refojo MF (1968) Alloplastic implants in corneal edema. Int Ophthalmol Clin 8: 729–756PubMedGoogle Scholar
  23. 23.
    Dohlman CH, Schneider HA, Doane MG (1974) Prosthokeratoplasty. Am J Ophthalmol 77: 694–700PubMedGoogle Scholar
  24. 24.
    Dohlman CH, Webster RG, Biswas SK, Refojo MF (1969) Prothèses cornéenes à double plaque maintenues à l’aide d’adhésifs chirugicaux. Arch Opht (Paris) 29: 169–174Google Scholar
  25. 25.
    Donn A (1976) Aphakic bullous keratopathy treated with prosthokeratoplasty. Arch Ophthalmol 94: 270–273PubMedGoogle Scholar
  26. 26.
    Donn A (1977) Symposium: Keratoprothesis. Additional follow-up of 34 cases of Prosthokeratoplasty. Amer Acad Oph talmol 83: 281Google Scholar
  27. 27.
    Dorzee MJ (1955) Keratoprothese en acrylique. Bull Soc belge ophthalmol 108: 582–593Google Scholar
  28. 28.
    Ferry AP, Gordon BL (1974) Epithelialization of the anterior Korund-chamber. A complication of prosthokeratoplasty. Arch Oph thalmol 91: 281–284Google Scholar
  29. 29.
    Filatov WP (1957) Zit. from Day R: Trans Am Ophthalmol and Soc 55: 455Google Scholar
  30. 30.
    Franceschetti A (1949) Corneal Grafting. Trans Ophthalmol Soc UK 69: 17–35Google Scholar
  31. 31.
    Girard LJ, Moore CD, Soper JW, O’Bannon W (1969) Pros thokeratoplasty–Implantation of a keratoprosthesis using full-thickness onlay sclera and sliding conjunctival flap. Transact Am Acad Ophthalmol 73: 936–961Google Scholar
  32. 32.
    Girard LJ, Hawkins RS, Nieves R, Borodofsky T, Grant C (1977) Keratoprothesis: a 12-year follow-up. Am Acad Oph thalmol 83: 252–267Google Scholar
  33. 33.
    Gundorova RA, Malaev AA (1975) A new method of corneal Augenheilk prosthetics in dealing with eye burns sequelae (preliminary communication). Vestn Oftalmol (Moskau) 2: 37–30Google Scholar
  34. 34.
    Gundorova RA, Malaev AA (1979) Remote results of optic prosthokeratoplasty. Oftalmol Zh 34: 396–399PubMedGoogle Scholar
  35. 35.
    Györffy J (1951) Acrylic corneal implant in keratoplasty. Am J Ophthalmol 34: 575–761.Google Scholar
  36. 36.
    Hatt M (1979) Experimental Osteokeratoprosthesis. Ophthal mic Res 11: 40–51CrossRefGoogle Scholar
  37. 37.
    Hayano S (1966) Histological study on a human cornea with a keratoprosthesis. Acta Soc Ophthalmol Jap 70: 2132Google Scholar
  38. 38.
    Heusser J (1860) Die Einheilung einer Cornea artificialis. report. Österr Z f prakt Med 26: 424Google Scholar
  39. 39.
    Hippel A v (1887) Über die operative Behandlung totaler sta- tionärer Hornhaut-Trübungen. Albrecht von Graefes Arch Ophthalmol 23 /11, 79–160Google Scholar
  40. 40.
    Hoffmann F, Harnisch J-P, Strunz V, Bunte M, Gross UM, Männer K, Brömer H, Deutscher K (1978) Osteo-Keramo Keratoprothese. Eine Modifikation der Osteo-Odonto-Kera- toprothese nach Strampelli. Klin Monatsbl Augenheilk 173: 747–755 41.Google Scholar
  41. 41.
    Krasnov MM, Orlova EM (1967) First experience with im plantation of artificial cornea (alloplastic keratoprostheses).Vestn Ophthalmol (Moskau) 10: 11–16Google Scholar
  42. 42.
    Krasnov MM, Udinstov BE, Malaeva LV (1979) Remote re- sults of penetrating autochondrokeratoprosthesing. Oftal Z34: 392–394Google Scholar
  43. 43.
    Lund O-E (1972) Kunststoff-Keratoplastik (Cornea artificia-lis). Vergangenheit und Gegenwart. Münchner Med Wo chenschr 23: 1115–1125Google Scholar
  44. 44.
    Lund O-E (1977) Die Keratoprothese. Ber Dtsch Ophthalmol Ges 75: 173–180 Cornea arteficialis.Google Scholar
  45. 45.
    Lund O-E (1980) Wundheilung nach Keratoprothese. In: GOH Naumann, B Gloor (Hrsg). Wundheilung des Auges und ihre Komplikationen. Bergmann, MünchenGoogle Scholar
  46. 46.
    Lund O-E (1982) Grenzen und Möglichkeiten der optischenKeratoprothese. Ein klinischer und histopathologischer Be-richt. Klin Monatsbl Augenheilk 180: 3–12CrossRefGoogle Scholar
  47. 47.
    Mester U (1979) Tierexperimentelle Ergebnisse mit Hydrogel-Keratoprothesen unterschiedlichen Wassergehaltes. Ophthal-mologica 179: 62–69CrossRefGoogle Scholar
  48. 48.
    Nussbaum NJ (1853) Cornea artificialis, ein Substitut für dieTransplantatio corneae. Deutsche Klinik 34: 367Google Scholar
  49. 49.
    Polack FM, Heimke G (1980) Keratoprothesen aus einkristall und -keramik. Ber Dtsch Ophthalmol Ges 77: 469–477Google Scholar
  50. 50.
    Puchkovskaya NA, Yakimenko SA (1976 a) Prevention treatment of complications after penetrating prosthokerato-plasty. Oftal Z 31: 563–569Google Scholar
  51. 51.
    Puchkovskaya NA, Yakimenko SA (1976 b) Two stage method of prosthokeratoplasty. Oftal Z 31: 497–500Google Scholar
  52. 52.
    Roper-Hall MJ (1980) Stallard’s Eye Surgery. Wright, BristolGoogle Scholar
  53. 53.
    Salzer F (1898) Über den künstlichen Hornhautersatz. Berg-mann, WiesbadenGoogle Scholar
  54. 54.
    Salzer F (1900) Über den weiteren Verlauf des in meiner Ar-beit über den künstlichen Hornhaut-Ersatz mitgeteilten Falles von Cornea arteficialis sowie des von Schröderschen Falles. Z III: 504–509Google Scholar
  55. 55.
    Schimmelpfennig B (1978) Tierexperimentelle Untersuchun-gen über die Gewebeverträglichkeit intrakornealer Hornlin-sen. Klin Monatsbl Augenheilk 172: 464–469Google Scholar
  56. 56.
    Smolin G, Thoft RA (1953) The Cornea. Little Brown, Boston TorontoGoogle Scholar
  57. 57.
    Sommer G (1953) Neue Versuche zur Alloplastik der Kornea Klin Monatsbl Augenheilk 122: 545Google Scholar
  58. 58.
    Sommer G (1979) Probleme und Entwicklungen der Kerato-prothetik. Klin Monatsbi Augenheilk 175: 851–856Google Scholar
  59. 59.
    Stone W jr, Herbert E (1953) Experimental study of plastic material as replacement for the cornea. A preliminary Am J Ophthalmol 36: 168Google Scholar
  60. 60.
    Stone W jr (1966) Plastic artificial cornea: sixteen year study. Exc Med Internat Congr Series 146: 848–849, 1966 Amsterdam, Excerpta MedicaGoogle Scholar
  61. 61.
    Strampelli B, Marchi V (1970) Osteo-Odonto-Keraprothesis. Ann Ott e Clin Ocul XCVI Parma No 1Google Scholar
  62. 62.
    Strampelli B (1974/75) Osteo-Odonto-Cheratoprotesi. Anales Inst Barraquer 12: 26–141Google Scholar
  63. 63.
    Strampelli B (1976) Symposium über Keratoprothese. Personal communication. 26. November FlorenzGoogle Scholar
  64. 64.
    Verhoeff FH (1962) Personal communication to Dr. AG de Voe. Quoted by CardonaGoogle Scholar
  65. 65.
    Volkov W, Ushakov NA (1976) Complication after penetrat-ing prosthokeratoplasty, their prevention and treatment. Oftal Z 31: 569–573Google Scholar
  66. 66.
    Weber A (1887) Quoted by A v Hippel. Über die operative Behandlung totaler stationärer Hornhauttrübungen. Albrecht v Graefes Arch Ophthalmol 23 /11, 79–160Google Scholar
  67. 67.
    Wünsche G (1947) Versuche zur totalen Keratoplastik und zur Ärztliche Forsch Heft 18 /19: 345–356Google Scholar
  68. 68.
    Zirm A (1906) Ene erfolgreiche totale Keratoplastik. Albrecht v Graefes Arch Ophthalmol 580–593Google Scholar
  69. 69.
    Symposium on Keratoprosthesis (1976) 81 Annual Meeting of the American Academy of Ophthalmology. Las Vegas, Oct 6–10Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • O.-E. Lund

There are no affiliations available

Personalised recommendations