Abstract
Psychopathologically defined diagnoses represent guidelines for the application of drugs and serve as selection criteria for the evaluation of potentially useful psychopharmacological agents. Therefore, the success of research in drug evaluation strongly depends on the conceptual frameworks of diagnostic classification and how these change. For instance, at the beginning of the era of antidepressants 30 years ago, the efficacy of antidepressants was thought to be restricted to patients with endogenous depression, but since then their therapeutic spectrum has broadened: first to the “depressive syndrome” and then, due to the growing acceptance of DSM-III, to the major depressive episode. Now, even further indications for antidepressants, especially for panic disorder and generalized anxiety disorder, have been suggested.
Dedicated to Professor Dr. Hanns Hippius on the occasion of his 65th birthday.
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Benkert, O. (1990). Functional Classification and Response to Psychotropic Drugs. In: Benkert, O., Maier, W., Rickels, K. (eds) Methodology of the Evaluation of Psychotropic Drugs. Psychopharmacology Series, vol 8. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75370-1_12
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