Results of the Whipple Procedure in Combination with Pancreatic Duct Occlusion

  • H. Zirngibl
  • F. P. Gall


The results of operative treatment of chronic pancreatitis are disappointing, as shown in a literature survey by Gebhardt [7] (Table 1). The reason for the high number of recurrences — 30%-50% following pancreatic drainage procedures and 20%–30% following resection — lies in the continuing, independently progressing inflammation in the residual pancreas. In about 10–15 years this leads to complete atrophy and to a tissue alteration of the exocrine pancreas parenchyma. In 1984, Ammann et al. [1] were able to show that burning out of the glands in alcohol-induced chronic pancreatitis, in addition to an increasing calcification parallel with a reduction in the endocrine reserve capacity, leads ultimately to insulin-dependent diabetes mellitus. Surgical therapy can thus eliminate only the consequences and complications but not the cause of the pancreatitis.


Chronic Pancreatitis Pancreatic Duct Whipple Procedure Disablement Retire Duct Occlusion 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • H. Zirngibl
  • F. P. Gall
    • 1
  1. 1.Department of Surgery, UniversitätsklinikFriedrich-Alexander University of Erlangen-NurembergErlangenGermany

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