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Results of the Whipple Procedure in Combination with Pancreatic Duct Occlusion

  • H. Zirngibl
  • F. P. Gall

Abstract

The results of operative treatment of chronic pancreatitis are disappointing, as shown in a literature survey by Gebhardt [7] (Table 1). The reason for the high number of recurrences — 30%-50% following pancreatic drainage procedures and 20%–30% following resection — lies in the continuing, independently progressing inflammation in the residual pancreas. In about 10–15 years this leads to complete atrophy and to a tissue alteration of the exocrine pancreas parenchyma. In 1984, Ammann et al. [1] were able to show that burning out of the glands in alcohol-induced chronic pancreatitis, in addition to an increasing calcification parallel with a reduction in the endocrine reserve capacity, leads ultimately to insulin-dependent diabetes mellitus. Surgical therapy can thus eliminate only the consequences and complications but not the cause of the pancreatitis.

Keywords

Chronic Pancreatitis Pancreatic Duct Whipple Procedure Disablement Retire Duct Occlusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • H. Zirngibl
  • F. P. Gall
    • 1
  1. 1.Department of Surgery, UniversitätsklinikFriedrich-Alexander University of Erlangen-NurembergErlangenGermany

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