Natural History and Long-Term Monitoring of Therapeutic Attempts to Eradicate Helicobacter pylori

  • E. A. J. Rauws
  • G. N. J. Tytgat
Conference paper

Abstract

Information about the natural history of H.pylori-associated gastritis is mainly obtained indirectly because without symptoms individuals are rarely endoscoped, and so infections may remain undiagnosed. To truly determine the natural history many persons, colonized or not colonized with H. pylori and with or without symptoms, should be followed up, including endoscopy and biopsies, without treatment. An alternative approach to study the significance of H. pylori is longterm follow-up of a substantial group of patients after eradication of these microorganisms.

Keywords

Formalin Bismuth Hematoxylin Tetracycline Eosin 

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References

  1. 1.
    Langenberg W, Rauws EAJ, Widjojokusomo A, Tytgat GNJ, Zanen HC (1986) Identification of Campylobacter pyloridis isolates by restriction endonuclease DNA analysis. J Clin Microbiol 24:414–417.PubMedGoogle Scholar
  2. 2.
    Langenberg W, Rauws EAJ, Houthoff HJ et al. (1988) Follow-up study of individuals with untreated Campylobacter pylori-associated gastritis and of noninfected persons with nonulcer dyspepsia. J Infect Dis 157:1245–1249.PubMedCrossRefGoogle Scholar
  3. 3.
    Marshall BJ, Armstrong JA, McGechie DB, Glancy RJ (1985) Attempt to fulfil Koch’s postulates for pyloric campylobacter. Med J Aust 142:436–439.PubMedGoogle Scholar
  4. 4.
    Rauws EAJ, Langenberg W, Houthoff HJ, Zanen HC, Tytgat GNJ (1988) Campylobacter pyloridis-associated chronic antral gastritis. Gastroenterology 94:33–40.PubMedGoogle Scholar
  5. 5.
    Siurala M, Vuorinen Y (1963) Follow-up studies of patients with superficial gastritis and patients with a normal gastric mucosa. Acta Med Scand 173:45–52.PubMedCrossRefGoogle Scholar
  6. 6.
    Ihamäki T, Saukkonen M, Siurala M (1978) Longterm observation of subjects with normal mucosa and with superficial gastritis. Results of 23–27 years follow-up examination. Scand J Gastroenterol 13:771–776.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • E. A. J. Rauws
    • 1
  • G. N. J. Tytgat
    • 1
  1. 1.Dept. of GastroenterologyAcademic Medical CenterAmsterdamNetherlands

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