Natural History and Long-Term Monitoring of Therapeutic Attempts to Eradicate Helicobacter pylori
Information about the natural history of H.pylori-associated gastritis is mainly obtained indirectly because without symptoms individuals are rarely endoscoped, and so infections may remain undiagnosed. To truly determine the natural history many persons, colonized or not colonized with H. pylori and with or without symptoms, should be followed up, including endoscopy and biopsies, without treatment. An alternative approach to study the significance of H. pylori is longterm follow-up of a substantial group of patients after eradication of these microorganisms.
KeywordsAtrophic Gastritis Nonulcer Dyspepsia Superficial Gastritis Pylorus Colonization Active Chronic Gastritis
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Langenberg W, Rauws EAJ, Widjojokusomo A, Tytgat GNJ, Zanen HC (1986) Identification of Campylobacter pyloridis isolates by restriction endonuclease DNA analysis. J Clin Microbiol 24:414–417.PubMedGoogle Scholar
Langenberg W, Rauws EAJ, Houthoff HJ et al. (1988) Follow-up study of individuals with untreated Campylobacter pylori-associated gastritis and of noninfected persons with nonulcer dyspepsia. J Infect Dis 157:1245–1249.PubMedCrossRefGoogle Scholar
Marshall BJ, Armstrong JA, McGechie DB, Glancy RJ (1985) Attempt to fulfil Koch’s postulates for pyloric campylobacter. Med J Aust 142:436–439.PubMedGoogle Scholar
Rauws EAJ, Langenberg W, Houthoff HJ, Zanen HC, Tytgat GNJ (1988) Campylobacter pyloridis-associated chronic antral gastritis. Gastroenterology 94:33–40.PubMedGoogle Scholar
Siurala M, Vuorinen Y (1963) Follow-up studies of patients with superficial gastritis and patients with a normal gastric mucosa. Acta Med Scand 173:45–52.PubMedCrossRefGoogle Scholar
Ihamäki T, Saukkonen M, Siurala M (1978) Longterm observation of subjects with normal mucosa and with superficial gastritis. Results of 23–27 years follow-up examination. Scand J Gastroenterol 13:771–776.PubMedCrossRefGoogle Scholar
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