Influence of Chronic Antral and Duodenal Inflammation on Motor Disorders
Motor disorders involving electrical control activity (ECA), fasting, and fed gastroduodenal motility and alteration in gastric emptying have been identified in patients with dyspeptic symptoms , chronic type B gastritis , and duodenogastric reflux . The most frequent abnormality of antroduodenal motility during fasting is a longer than normal duration of migrating myoelectrical complexes (MMCs) mainly due to a prolongation of phase II and shortening of phase I activity . This abnormality should increase the possibility of generating a gastroduodenal bile reflux which was earlier considered to be the main pathophysiologic process involved in the genesis of chronic gastritis. The demonstration that MMC prolongation and duodenogastric reflux is present also in patients without gastritis  may suggest the hypothesis that gastritis is more a consequence than cause of the motor abnormality, such as in case with esophagitis and of gastroesophageal reflux.
KeywordsGastritis Esophagitis Dyspepsia Duodenitis
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