Skip to main content

Gastroduodenal Motility in Relation to Peptic Ulcer Pathogenesis and Helicobacter pylori Infection

  • Conference paper

Abstract

Multiple factors and in varying degrees are involved in the etiology of peptic uleer disease. Gastric acid secretion, mucosal defense mechanisms, gut hormones (i.e., hypergastrinemia), and motor disorders of the upper gastrointestinal tract have been associated with the pathogenesis of peptic ulcer. The relevance of motility disorders, however, as well as their cause-effect relationship in the pathogenesis of ulcers are still unclear.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Miranda M, Defilippi C, Valenzuela JE (1985) Abnormalities of interdigestive motility complex and increased duodenogastric reflux in gastric ulcer patients. Dig Dis Sci 30:16–21.

    Article  PubMed  CAS  Google Scholar 

  2. Garret JM, Summerskill WHJ, Code CF (1966) Antral motility in patients with gastric ulcer. Am J Dig Dis 11:780–789.

    Article  Google Scholar 

  3. Sarna S (1985) Cyclic motor activity; migrating motor complex. Gastroenterology 89:894–913.

    PubMed  CAS  Google Scholar 

  4. Code CF, Marlett JA (1975) The interdigestive myoelectric complex of the stomach and small bowel of dogs. J Physiol (Lond) 246:289–309.

    CAS  Google Scholar 

  5. Miller CJ, Malagelada JR, Longstreth GF, Go VLW (1980) Dysfunctions of the stomach with gastric ulceration. Dig Dis Sci 25:857–864.

    Article  PubMed  CAS  Google Scholar 

  6. Minami H, McCallum RW (1984) The physiology and pathophysiology of gastric emptying in humans. Gastroenterology 86:1592–1610.

    PubMed  CAS  Google Scholar 

  7. Bortolotti M (1989) Interdigestive gastroduodenal motility in duodenal ulcer: role of gastric acid hypersecretion. Am J Gastroenterol 84:17–21.

    PubMed  CAS  Google Scholar 

  8. Itoh Z, Sekiguchi T (1983) Interdigestive motor activity in health and disease. Scand J Gastroenterol [Suppl] 121-134, Vol. 18, Suppl. 87.

    Article  Google Scholar 

  9. Borgstrom S, Arborelius M (1978) Duodenal motility pattern in duodenal ulcer disease. Scand J Gastroenterol 13:349–352.

    Article  PubMed  CAS  Google Scholar 

  10. Johnson AG (1979) Peptic ulcer and the pylorus. Lancet 1:710–712.

    Article  PubMed  CAS  Google Scholar 

  11. Maddern GJ, Horowitz M, Hetzel DJ, Jamieson GG (1985) Altered solid and liquid gastric emptying in patients with duodenal ulcer disease. Gut 26:689–693.

    Article  PubMed  CAS  Google Scholar 

  12. Moore JG, Mclntyre B, Alazraki N (1985) Gastric emptying of combined liquid-solid meals in healed duodenal ulcer. Dig Dis Sci 30:1134–1138.

    Article  PubMed  CAS  Google Scholar 

  13. Williams NS, Elashoff J, Meyer JH (1986) Gastric emptying of liquids in normal subjects and patients with healed duodenal ulcer disease. Dig Dis Sci 31:943–952.

    Article  PubMed  CAS  Google Scholar 

  14. Griffith EH, Owen GM, Campbell H (1968) Gastric emptying in health and in gastroduodenal disease. Gastroenterology 54:1–7.

    PubMed  CAS  Google Scholar 

  15. Cobb JS, Bank S, Marks IN (1971) Gastric emptying after vagotomy and pyloroplasty. Am J Dig Dis 16:207–215.

    Article  PubMed  CAS  Google Scholar 

  16. Malagelada JR, Longstreth GF, Deering TB, Summerskill WHJ, Go VLW (1977) Gastric secretion and emptying after ordinary meals in duodenal ulcer. Gastroenterology 73:989–994.

    PubMed  CAS  Google Scholar 

  17. Lam SK, Istenberg JI, Grossman MI, Lane WH, Hogan DL (1982) Rapid gastric emptying in duodenal ulcer patients. Dig Dis Sci 27:598–604.

    Article  PubMed  CAS  Google Scholar 

  18. Warren JR, Marshall BJ (1983) Unidentified curved bacilli on gastric epithelium in active chronic gastritis. Lancet 1:1273–1275.

    Google Scholar 

  19. Blaser MJ (1985) Gastritis Campylobacter-like organisms, gastritis and peptic ulcer disease. Gastroenterology 93:371–383.

    Google Scholar 

  20. Malagelada JR, Stanghellini V (1985) Manometric diagnosis of the motor disturbances of the upper gastrointestinal tract. Gastroenterology 88:1225–1231.

    Google Scholar 

  21. Pieramico O, Wilberg S, Glasbrenner B, Malfertheiner P (1989) Antroduodenal motility in Campylobacter pylori associated chronic type B gastritis. Klin Wochenschr [Suppl 18] 67:54.

    Google Scholar 

  22. Moore SC, Malagelada JR, Shorter RG, Zinsmeister AR (1986) Interrelationship among gastric mucosal morphology, secretion, and motility in peptic ulcer disease. Dig Dis Sci 31:673–684.

    Article  PubMed  CAS  Google Scholar 

  23. Wilberg S, Pieramico O, Malfertheiner P (1989) Role of antral inflammation on orocecal transit time in patients with non-ulcer dyspepsia. Klin Wochenschr [Suppl 18] 67:72.

    Google Scholar 

  24. Holt S, Heading RC, Taylor TV, Forrest JA, Tothill P (1986) Is gastric emptying abnormal in duodenal ulcer? Dig Dis Sci 31:685–692.

    Article  PubMed  CAS  Google Scholar 

  25. Wegener M, Borsch G, Schaffstein J, Schulz-Flache C, Mai U, Leverkus F (1988) Are dyspeptic symptoms in patients with Campylobacter pylori-associated Type B gastritis linked to delayed gastric emptying? Am J Gastroenterol 83:737–740.

    PubMed  CAS  Google Scholar 

  26. Prakash C, Marshall BJ, Plankey MW, Guerrant R, McCallum RW (1987) Gastric emptying of solids in patients with Campylobacter pylori gastritis. Am J Gastroenterol 32:935.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Pieramico, O., Malfertheiner, P. (1990). Gastroduodenal Motility in Relation to Peptic Ulcer Pathogenesis and Helicobacter pylori Infection. In: Malfertheiner, P., Ditschuneit, H. (eds) Helicobacter pylori, Gastritis and Peptic Ulcer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75315-2_44

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-75315-2_44

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75317-6

  • Online ISBN: 978-3-642-75315-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics