Abstract
In 1984, Marshall and Warren [10] reported the presence of spiral organisms in the gastric mucosa of adults with gastritis. Since then, this organism has been isolated and characterized as Helicobacter pylori (H. pylori). A number of investigators have reported an association between H. pylori and gastritis or gastric and duodenal ulcers in adults [6, 7, 13]. With the advent of small flexible fiber-optic endoscopes, several pediatric studies have investigated the relationship of H. pylori infection and gastritis [2–4]. In industrialized countries, H. pylori infection is a rare finding in the gastric mucosa of children. The low prevalence as well as the lack of confounding variables such as smoking, alcohol intake, or use of nonsteroidal antiinflammatory drugs (NSAIDS) in children may allow such pediatric studies of clarify the role of H. pylori in the pathogenesis of gastritis and gastric or duodenal ulcers. The purpose of the present study was: (a) to determine the relationship between H. pylori and gastritis or peptic ulcer disease in children and (b) to determine the natural history of H. pylori in children with gastritis.
This work was supported in part, by Grant AI 25818 from the National Institute of Allergy and Infectious Diseases.
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© 1990 Springer-Verlag Berlin Heidelberg
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Czinn, S.J. (1990). Helicobacter pylori Induced Gastritis in Childhood. In: Malfertheiner, P., Ditschuneit, H. (eds) Helicobacter pylori, Gastritis and Peptic Ulcer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75315-2_29
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DOI: https://doi.org/10.1007/978-3-642-75315-2_29
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