Local Immune Responses to Helicobacter pylori Infections
It is widely accepted that the majority of people with H. pylori infections amount a large circulating antibody response against that organism . This response has proved to be so predictable that it forms the basis of serodiagnostic tests such as ELISA [2, 3]. The sensitivity and specificity of such tests depends largely on the antigen preparations used, although ELISAs using a variety of crude and more purified antigens are reported to be greater than 90 % sensitive and specific for detecting H. pylori infection [4, 5].
KeywordsGastritis Dyspepsia Duodenitis
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- 9.Newell DG, Stacey AR (1989) The isotype and specificity of local and systemic anti-Campylobacter pylori antibodies. Proceedings of the second international symposium on Campylobacter pylori. Bad Nauheim, Springer, Berlin Heidelberg New York (in press)Google Scholar
- 10.Crabtree JE, Rathbone BJ, Shallcross T, Wyatt JL, Heatley RV (1989) Local humoral responses to Campylobacter pylori in patients with duodenitis. Poster presentation, 2nd Meeting of the European Campylobacter pylori Study Group, Ulm.Google Scholar
- 12.Stacey AR, Newell DG (1989) The development of antigens for improved serodiagnostic tests of Campylobacter pylori-associated gastritis. In: Mégraud F, Lamouliatte H (eds) Proceedings of the workshop of gastroduodenal pathology and Campylobacter pylori, Bordeaux. Elsevier, Amsterdam, p 193.Google Scholar