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The Structure of Helicobacter pylori Urease

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Book cover Helicobacter pylori, Gastritis and Peptic Ulcer

Abstract

The urease is a prominent differential characteristic of Helicobacter pylori which is employed in diagnostic tests such as the C13/C14 breath test, serodiagnosis and the rapid CLO tests. The role of the enzyme is, as yet, unclear. The number of different ureolytic bacteria being found on the gastric mucosa of various hosts is increasing, raising the question of whether the ureases of these organisms are related.

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References

  1. Newell DG (1987) Identification of the outer membrane proteins of Campylobacter pyloridis and antigenic cross-reactivity between C. pyloridis and C. jejuni. J Gen Microbiol 133:163–170.

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  2. Newell DG, Lee A, Hawtin PR, Hudson MJ, Stacey AR and Fox J (1989) Antigenic conservation of the ureases of spiral — and helical — shaped bacteria colonising the stomachs of man and animals. 65:183–186.

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© 1990 Springer-Verlag Berlin Heidelberg

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Hawtin, P.R., Stacey, A.R., Newell, D.G. (1990). The Structure of Helicobacter pylori Urease. In: Malfertheiner, P., Ditschuneit, H. (eds) Helicobacter pylori, Gastritis and Peptic Ulcer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75315-2_12

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  • DOI: https://doi.org/10.1007/978-3-642-75315-2_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75317-6

  • Online ISBN: 978-3-642-75315-2

  • eBook Packages: Springer Book Archive

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