State of the Art: Pancreatic Transplantation
Pancreas transplants have been performed at the University of Minnesota since 1966 . The results of the first series of 14 transplants, ending in 1973, have been reported in detail [2, 3]. In 1978 pancreas transplants were resumed at the University of Minnesota , first in diabetic patients who already had kidney transplants, then in nonuremic non-kidney transplant patients [5–7], and finally in uremic or preuremic recipients of simultaneous kidney transplants . The grafts have been procured from living related and cadaver donors . We have tested a variety of surgical techniques [6, 10] and immunosuppressive regimens [6, 8]. This paper summarizes our overall, initial, and most recent results according to multiple variables.
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- 1.Kelley WD, Lillehei RC, Merkel FK et al. (1987) Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy. Surgery 61: 827Google Scholar
- 3.Lillehei RC, Ruiz JO, Acquino C et al. (1976) Transplantation of the pancreas. Acta Ebdicrebik 83 [Suppl 205]: 303Google Scholar
- 7.Sutherland DER, Kendall DM, Moudry KC, Navarro X, Kennedy WR, Ramsay RC, Steffes MW, Mauer SM, Goetz FC, Dunn DL, Najarian JS (1988) Pancreas transplantation in nonuremic, type I diabetic recipients. Surgery 102: 453–464Google Scholar
- 8.Sutherland DER, Goetz FC, Moudry KC, Najarian JS (1988) Pancreatic transplantation — a single institution’s experience. Diabetes, nutrition and metabolism 1: 57–64Google Scholar
- 14.DeFrancisco AM, Mauer SM, Steffes MW, Goetz FC, Najarian JS, Sutherland DER (1987) The effect of cyclosporine on native renal function in nonuremic diabetic recipients of pancreas transplants. J Diab Compl 1: 128–131Google Scholar