Human T-Cell Memory

  • P. C. L. Beverley
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 159)


The specificity and memory of immune responses sets them apart from all other physiological responses except those of the nervous system. These properties have long been recognised by immunologists, and while specificity is well accounted for by clonally distributed B- and T-cell receptors, the nature of immunological memory still poses many problems. While it has often been assumed that memory cells are long-lived and not dependent on continuous or repeated antigenic stimulation, this view has been challenged by recent data which suggest that persistence of memory is dependent on continued antigen drive (Gray and Skarvall 1988).


Soluble Antigen CD45 Isoforms Immunoglobulin Synthesis Limit Dilution Analysis Leucocyte Common Antigen 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • P. C. L. Beverley
    • 1
  1. 1.Imperial Cancer Research Fund Human Tumour Immunology GroupUniversity College and Middlesex School of Medicine, The Courtauld Institute of BiochemistryLondonUK

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