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Human T-Cell Memory

  • Conference paper
Immunological Memory

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 159))

Abstract

The specificity and memory of immune responses sets them apart from all other physiological responses except those of the nervous system. These properties have long been recognised by immunologists, and while specificity is well accounted for by clonally distributed B- and T-cell receptors, the nature of immunological memory still poses many problems. While it has often been assumed that memory cells are long-lived and not dependent on continuous or repeated antigenic stimulation, this view has been challenged by recent data which suggest that persistence of memory is dependent on continued antigen drive (Gray and Skarvall 1988).

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Authors and Affiliations

  1. Imperial Cancer Research Fund Human Tumour Immunology Group, University College and Middlesex School of Medicine, The Courtauld Institute of Biochemistry, 91 Riding House Street, London, WIP 8BT, UK

    P. C. L. Beverley

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  1. P. C. L. Beverley
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Editors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstr. 487, CH-4005, Basel, Switzerland

    David Gray Ph.D.

  2. Dept. of immunology-IMM4A, Research Inst. of Scripps Clinic, 10666 North Torrey Pines Road, La Jolla, CA, 92037, USA

    Jonathan Sprent M.B., B.S., Ph.D. (Member) (Member)

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© 1990 Springer-Verlag Berlin Heidelberg

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Beverley, P.C.L. (1990). Human T-Cell Memory. In: Gray, D., Sprent, J. (eds) Immunological Memory. Current Topics in Microbiology and Immunology, vol 159. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75244-5_7

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  • DOI: https://doi.org/10.1007/978-3-642-75244-5_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75246-9

  • Online ISBN: 978-3-642-75244-5

  • eBook Packages: Springer Book Archive

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