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The Generation of B-Cell Memory: A Working Hypothesis

  • Conference paper
Immunological Memory

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 159))

Abstract

The process by which secondary B cells are generated has intrigued immunologists for several decades. This is particularly true since appropriate antigenic stimulation leads both to a selective increase in the frequency of B cells responsive to the immunizing antigen and to the generation of a population of cells (secondary B cells) that are phenotypically and functionally distinct from primary B cells specific for the same antigen.

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Author information

Authors and Affiliations

  1. Department of Immunology, Research Institute of Scripps Clinic, La Jolla, CA, 92037, USA

    N. R. Klinman & P.-J. Linton

Authors
  1. N. R. Klinman
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  2. P.-J. Linton
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Editor information

Editors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstr. 487, CH-4005, Basel, Switzerland

    David Gray Ph.D.

  2. Dept. of immunology-IMM4A, Research Inst. of Scripps Clinic, 10666 North Torrey Pines Road, La Jolla, CA, 92037, USA

    Jonathan Sprent M.B., B.S., Ph.D. (Member) (Member)

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© 1990 Springer-Verlag Berlin Heidelberg

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Klinman, N.R., Linton, PJ. (1990). The Generation of B-Cell Memory: A Working Hypothesis. In: Gray, D., Sprent, J. (eds) Immunological Memory. Current Topics in Microbiology and Immunology, vol 159. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75244-5_2

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  • DOI: https://doi.org/10.1007/978-3-642-75244-5_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75246-9

  • Online ISBN: 978-3-642-75244-5

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