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Essential Genes for Development ofDictyostelium

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Progress in Molecular and Subcellular Biology

Part of the book series: Progress in Molecular and Subcellular Biology ((PMSB,volume 11))

Abstract

A long-term dream of many molecular developmental biologists is to recognize the temporal sequence of gene expression that directs the morphogenetic stages of embryogenesis. In a few species that are amenable to high resolution genetics the pieces are beginning to fall into place. Specific molecular differentiations can now be seen to define the outlines of the physiological changes that direct development. For instance, the combination of classical and molecular genetics in the fruitfuly Drosophila has lead to a dramatic increase in understanding the role of well-defined genes in establishing the segmental pattern of embryos and larva. A few dozen maternal genes control the temporal and spatial patterns of expression of another few dozen zygotically expressed genes (Ingham 1988). Structures specific to each segment are then made in the appropriate segments. Exactly how these decisions are made is still poorly understood, but it is a satisfying advance just to be able to name the genes and know their nucleotide sequences. Connecting this primary sequence data to three dimensional differentiations requires other approaches that are hampered in Drosophila by the complexity of the embryos. It is difficult to analyze the interaction of gene products that are functioning differently in different compartments, and are present in different ratios at different times. The goal of understanding all of the genes that play major roles in fly embryogenesis will require continued brilliance and stamina for many years to come.

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References

  • Ashworth J, Quance J (1972) Enzyme synthesis in myxamoebae of the cellular slime mold Dictyostelium discoideum during growth in axenic culture. Biochem J 126:601–608

    PubMed  CAS  Google Scholar 

  • Barklis E, Lodish HF (1983) Regulation of Dictyostelium discoideum mRNAs specific for prespore or prestalk cells. Cell 32:1139–1148

    Article  PubMed  CAS  Google Scholar 

  • Barra J, Barrand P, Blondelet M, Brachet p (1980) PdsA, a gene involved in the production of active phosphodiesterase during starvation of Dictyostelium discoideum amoebae. Mol Gen Genet 177:607–614

    Article  PubMed  CAS  Google Scholar 

  • Blumberg D, Margolskee J, Chung S, Barklis E, Cohen N, Lodish H (1982) Specific cell-cell contacts are essential for induction of gene expression during differentiation of Dictyostelium discoideum. Proc Natl Acad Sci 79:127–133

    Article  PubMed  CAS  Google Scholar 

  • Brookman J, Town C, Jermyn K, Kay R (1982) Developmental regulation of a stalk cell differentiation-inducing factor in Dictyostelium discoideum. Dev Biol 91:191–196

    Article  PubMed  CAS  Google Scholar 

  • Brookman J, Jermyn K, Kay R (1987) Nature and distribution of the morphogen DIF in Dictyostelium slugs. Development 100:119–124

    PubMed  CAS  Google Scholar 

  • Burns R, Livi G, Dimond R (1981) Regulation and secretion of early developmentally controlled enzymes during axenic growth in Dictyostelium discoideum. Dev Biol 83:407–416

    Article  Google Scholar 

  • Cardelli JA, Knecht DA, Wunderlich R, Dimond, RL (1985) Major changes in gene expression occur during at least four stages of development of Dictyostelium discoideum. Dev Biol 110:147–156

    Article  PubMed  CAS  Google Scholar 

  • Ceccarelli A, McRobbie S, Jermyn K, Duffy K, Early A, Williams J (1987) Structural and functional characterization of the Dictyostelium gene encoding a DIF inducible pre-stalkenriched mRNA sequence. Nucl Acids Res 15:7463–7476

    Article  PubMed  CAS  Google Scholar 

  • Chisholm RL, Barklis E, Lodish HF (1984) Mechanism of sequential induction of cell-type specific mRNAs in Dictyostelium differentiation. Nature 310:67–69

    Article  PubMed  CAS  Google Scholar 

  • Clarke M, Kayman S, Riley K (1987) Density-dependent inductor of discoidin-1 synthesis in exponentially growing cells of Dictyostelium discoideum. Differentiation 34:79–87

    Article  PubMed  CAS  Google Scholar 

  • Coloma A, Lodish H (1981) Synthesis of spore-specific and stalk-specific proteins during differentiation of Dictyostelium discoideum. Dev Biol 81:238–251

    Article  PubMed  CAS  Google Scholar 

  • Devine KM, Loomis WF (1985) Molecular characterization of anterior-like cells in Dictyostelium discoideum. Dev Biol 109:364–372

    Article  Google Scholar 

  • Devine KM, Morrissey J, Loomis WF (1982) Differential synthesis of spore coat proteins in prespore and prestalk cells of Dictyostelium. Proc Natl Acad Sci USA 79:7361–7365

    Article  PubMed  CAS  Google Scholar 

  • Devine K, Bergmann J, Loomis WF (1983) The spore coat proteins of Dictyostelium discoideum are packaged in prespore vesicles. Dev Biol 99:437–446

    Article  PubMed  CAS  Google Scholar 

  • Dimond RL, Loomis WF (1976) The structure and function of ß-glucosidases in Dictyostelium discoideum. J Biol Chem 251:2680–2687

    PubMed  CAS  Google Scholar 

  • Dimond RL, Brenner M, Loomis WF (1973) Mutations affecting N-acetylglucosaminidase in Dictyostelium discoideum. Proc Natl Acad Sci 70:3356–3360

    Article  PubMed  CAS  Google Scholar 

  • Dimond RL, Farnsworth P, Loomis WF (1976) Isolation and characterization of mutations affecting UDPG pyrophosphorylase in Dictyostelium discoideum. Dev Biol 50:169–181

    Article  PubMed  CAS  Google Scholar 

  • Early A, Williams J (1988) A Dictyostelium prespore-specific gene is transcriptionally repressed by DIF in vitro. Development 103:519–524

    PubMed  CAS  Google Scholar 

  • Early A, Williams J, Meyer H, Por S, Smith E, Williams K, Gooley A (1988) Structural characterization of the Dictyostelium discoideum prespore-specific gene D19 and its product, the cell surface glycoprotein PsA. Mol Cell Biol 8:3458–3466

    PubMed  CAS  Google Scholar 

  • Erdos G, West C (1989) Formation and organization of the spore coat of Dictyostelium discoideum. Exp Mycol 13:169–182

    Article  CAS  Google Scholar 

  • Faure M, Podgorski G, Franke J, Kessin R (1989) Rescue of a Dictyostelium discoideum mutant defective in cyclic nucleotide phosphodiesterase. Dev Biol 131:366–372

    Article  PubMed  CAS  Google Scholar 

  • Finney RE, Langtimm CJ, Soll DR (1985) Regulation of protein synthesis during the preaggregative period of Dictyostelium discoideum development: involvement of close cell associations and cAMP. Dev Biol 110:171–191

    Article  PubMed  CAS  Google Scholar 

  • Firtel R (1972) Changes in the expression of single-copy DNA during development of Dictyostelium discoideum. J Mol Biol 66:363–377

    Article  PubMed  CAS  Google Scholar 

  • Fosnaugh C, Loomis WF (1989) The spore coat genes, SP60 and SP70, of Dictyostelium discoideum. Mol Cell Biol 9:5215–5218

    PubMed  CAS  Google Scholar 

  • Free S, Schimke R, Loomis WF (1976) The structural gene for a-mannosidase-1 in Dictyostelium discoideum. Genetics 84:159–174

    PubMed  CAS  Google Scholar 

  • Garrod D, Ashworth J (1972) Effect of growth conditions on development of the cellular slime mould, Dictyostelium discoideum. J Embryol Exp Morphol 28:463–479

    PubMed  CAS  Google Scholar 

  • Gerisch G (1987) Cyclic AMP and other signals controlling cell development and differentiation in Dictyostelium. Annu Rev Biochem 56:853–79

    Article  PubMed  CAS  Google Scholar 

  • Gerisch G, Fromm H, Huesgen A, Wick U (1975) Control of cell contact sites by cyclic AMP pulses in differentiating Dictyostelium cells. Nature 255:547–549

    Article  PubMed  CAS  Google Scholar 

  • Gomer RH, Firtel RA (1987) Cell-autonomous determination of cell-type choice in Dictyostelium development by cell-cycle phase. Science 237:758–762

    Article  PubMed  CAS  Google Scholar 

  • Grabel L, Loomis WF (1977) Cellular interaction regulating early biochemical differentiation in Dictyostelium. In: Cappucinelli P (ed) Development and Differentiation in Cellular Slime Molds. Elsevier, Amsterdam, pp 189–199

    Google Scholar 

  • Grabel L, Loomis WF(1978) Effector controlling accumulation of N-acetylglucosaminidase during development of Dictyostelium discoideum. Dev Biol 64:203–209

    Article  PubMed  CAS  Google Scholar 

  • Grossman A, Losick R (1988) Extracellular control of spore formation in Bacillus subtilis. Proc Natl Acad Sci (USA) 85:4369–4375

    Article  CAS  Google Scholar 

  • Haribabu B, Rajkovic A, Dottin R (1986) Cell-cell contact and cAMP regulate the expression of a UDP glucose pyrophosphorylase gene of Dictyostelium discoideum. Dev Biol 113:436–442

    Article  PubMed  CAS  Google Scholar 

  • Ingham P (1988) The molecular genetics of embryonic pattern formation in Drosophila. Nature 335:25–34

    Article  PubMed  CAS  Google Scholar 

  • Janssens P, van Haastert PJM (1987) Molecular basis of transmembrane signal transduction in Dictyostelium discoideum. Microbiol Rev 51:396–418

    PubMed  CAS  Google Scholar 

  • Kakutani T, Takeuchi I (1988) Characterization of anterior-like cells in Dictyostelium as analyzed by their movement. Dev Biol 115:439–445

    Article  Google Scholar 

  • Kimmel A, Firtel R (1982) The organization and expression of the Dictyostelium genome. In: Loomis WF (ed) The Development of Dictyostelium. Academic Press, San Diego CA.

    Google Scholar 

  • Klein C (1976) Adenylate cyclase activity in Dictyostelium discoideum amoebae and its changes during differentiation, FEBS Lett 68:125–127

    Article  PubMed  CAS  Google Scholar 

  • Klein C, Brachet P, Darmon M (1977) Periodic changes in adenylate cyclase and cAMP receptors in Dictyostelium discoideum. FEBS Lett 76:145–149

    Article  PubMed  CAS  Google Scholar 

  • Klein P, Sun T, Saxe C, Kimmel A, Johnson R, Devreotes P (1988) A chemoattractant receptor controls development in Dictyostelium discoideum. Science 241:1467–1472

    Article  PubMed  CAS  Google Scholar 

  • Knecht DA, Loomis WF (1987) Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum. Science 236:1081–1086

    Article  PubMed  CAS  Google Scholar 

  • Knecht DA, Loomis WF (1988) Developmental consequences of the lack of myosin heavy chain in Dictyostelium discoideum. Dev Biol 128:178–184

    Article  PubMed  CAS  Google Scholar 

  • Knecht DA, Cohen S, Loomis WF, Lodish HF (1986) Developmental regulation of Dictyostelium actin gene fusions carried on low-copy and high copy transformation vectors. Mol Cell Biol 6:3973–3983

    PubMed  CAS  Google Scholar 

  • Knecht DA, Fuller D, Loomis WF (1987) Surface glycoprotein, gp24, involved in early adhesion of Dictyostelium discoideum. Dev Biol 121:277–283

    Article  PubMed  CAS  Google Scholar 

  • Knecht DA, Fuller D, Loomis WF (1987) Surface glycoprotein, gp24, involved in early adhesion of Dictyostelium discoideum. Dev Biol 121:277–283

    Article  PubMed  CAS  Google Scholar 

  • Kopachik W, Oohata A, Dhokia B, Brookman J, Kay R (1983) Dictyostelium mutants lacking DIF, a putative morphogen. Cell 33:397–403

    Article  PubMed  CAS  Google Scholar 

  • Kumagai A, Pupillo M, Gunderson R, Miake-Lye R, Devreotes P, Firtel R (1989) Regulation and function of Ga protein subunits in Dictyostelium. Cell 57:265–275

    Article  PubMed  CAS  Google Scholar 

  • Kwong L, Weeks G (1989) Studies on the accumulation of the Differentiation Inducing Factor (DIF) in high cell density monolayers of Dictyostelium discoideum. Dev Biol 132:554–558

    Article  PubMed  CAS  Google Scholar 

  • Leach C, Ashworth J, Garrod D (1973) Cell sorting out during the differentiation of mixtures of metabolically distinct populations of Dictyostelium discoideum. J Embryol Exp Morphol 29:647–661

    PubMed  CAS  Google Scholar 

  • Loomis WF (1972) Role of surface sheath in the control of morphogenesis in Dictyostelium discoideum. Nature 240:6–9

    Google Scholar 

  • Loomis WF (1975) Dictyostelium discoideum: a developmental system. Academic Press, New York

    Google Scholar 

  • Loomis WF (1977). The number of developmental genes in Dictyostelium. Birth Defects 14:497–505

    Google Scholar 

  • Loomis WF (1982) The Development of Dictyostelium. Academic Press, New York

    Google Scholar 

  • Loomis WF (1985) Regulation of cell-type-specific differentiation in Dictyostelium. Cold Spring Harbour Symp Quant Biol 50:769–777

    CAS  Google Scholar 

  • Loomis WF (1987) Genetic tools for Dictyostelium discoideum. Methods Cell Biol 28:31–65

    Article  PubMed  CAS  Google Scholar 

  • Loomis WF (1988) Cell-cell adhesion in Dictyostelium discoideum. Dev Gen 9:549–559

    Article  CAS  Google Scholar 

  • Loomis WF, White S, Dimond RL (1976) A sequence of dependent stages in development of Dictyostelium discoideum. Dev Biol 53:171–177

    Article  PubMed  CAS  Google Scholar 

  • Loomis WF, Klein C, Brachet P (1978) The effect of divalent cations on aggregation of Dictvostelium discoideum. Differentiation 12:83–89

    Article  PubMed  CAS  Google Scholar 

  • Loomis WF, Wheeler SA, Springer W, Barondes S (1985) Adhesion mutants of Dictyostelium discoideum lacking the saccharide determinant recognized by two adhesion blocking monoclonal antibodies. Dev Biol 109:111–117

    Article  PubMed  CAS  Google Scholar 

  • Loomis WF, Knecht D, Fuller D (1987) Adhesion mechanisms and multicellular control of cell- type divergence of Dictyostelium discoideum. UCLA Symp Mol Cell Biol 51:399–349

    Google Scholar 

  • Mann S, Pinko C, Firtel R (1988) cAMP regulation of early gene expression in signal transduction mutants of Dict yostelium. Dev Biol 130:294–303

    Article  PubMed  CAS  Google Scholar 

  • Marin F (1976) Regulation of development in Dictyostelium discoideum. Part 1 Initiation of the growth to development transition by amino-acid starvation. Dev Biol 48:110–117

    Article  PubMed  CAS  Google Scholar 

  • Marin F (1977) Regulation of development in Dictyostelium discoideum. Part 2 Regulation of early cell differentiation by amino-acid starvation and inter-cellular interaction. Dev Biol 60:389–395

    Article  PubMed  CAS  Google Scholar 

  • McDonald SA (1984) Cell-cycle regulation of center initiation in Dictyostelium discoideum. Dev Biol 117:546–549

    Article  Google Scholar 

  • Mehdy MC, Firtel RA (1983) A secreted factor and cycle AMP jointly regulate cell-type-specific gene expression in Dictyostelium discoideum. Mol Cell Biol 5:705–713

    Google Scholar 

  • Mehdy MC, Ratner D, Firtel RA (1983) Induction and modulation of cell-type-specific gene expression in Dictyostelium. Cell 32:763–771

    Article  PubMed  CAS  Google Scholar 

  • Meinhardt H (1983) A model for the prestalk/prespore patterning in the slug of the slime mold Dictyostelium discoideum. Differentiation 24:191–202

    Article  PubMed  CAS  Google Scholar 

  • Morris H, Taylor G, Masento M, Jermyn K, Kay R (1987) Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum. Nature 328:811–814

    Article  PubMed  CAS  Google Scholar 

  • Morrissey J, Loomis WF (1981) Parasexual genetic analysis of cell proportioning mutants of Dictyostelium discoideum. Genetics 99:183–196

    PubMed  CAS  Google Scholar 

  • Morrissey J, Farnsworth P, Loomis WF (1981) Pattern formation in Dictyostelium discoideum: an analysis of mutants altered in cell proportioning. Dev Biol 83:1–8

    Article  PubMed  CAS  Google Scholar 

  • Morrissey J, Devine K, Loomis WF (1984) The timing of cell type specific differentiation in Dictyostelium discoideum. Dev Biol 103:414–424

    Article  PubMed  CAS  Google Scholar 

  • Murray B, Yee L, Loomis WF (1981) Immunological analysis of a glycoprotein (contact sites A) involved in intercellular adhesion of Dictyostelium discoideum. Supramol Struct Cell Biochem 17:387–401

    Google Scholar 

  • Murray B, Niman H, Loomis WF (1983) A monoclonal antibody recognizing gp80, a membrane glycoprotein implicated in intercellular adhesion of Dictyostelium discoideum. Mol Cell Biol 3:863–870

    PubMed  CAS  Google Scholar 

  • Murray BA, Wheeler S, Jongens T, Loomis WF (1984). Mutations affecting a surface glycoprotein, gp80, of Dictyostelium discoideum. Mol Cell Biol 4:514–519

    PubMed  CAS  Google Scholar 

  • Nellen W, Silan C, Firtel RA (1984) DNA-mediated transformation in Dictyostelium discoideum: regulated expression of an actin fusion. Mol Cell Biol 4:2890–2898

    PubMed  CAS  Google Scholar 

  • Odell G, Boner J (1986) How the Dictyostelium discoideum grex crawls. Philos Trans R Soc Lon Sec B 312:487–525

    Article  Google Scholar 

  • Orlowski M, Loomis WF (1979) Plasma membrane proteins of Dictyostelium: the spore coat proteins. Dev Biol 71:297–307

    Article  PubMed  CAS  Google Scholar 

  • Peters D, Knecht DA, Loomis WF, DeLozanne A, Spudich J, Van Haasert PJM (1988) Transmembrane signal transduction, chemotaxis and cell aggregation in Dictyostelium discoideum cells without myosin heavy chain. Dev Biol 128:158–163

    Article  PubMed  CAS  Google Scholar 

  • Raper K (1935) Dictyostelium discoideum, a new species of slime mold from decaying forest leaves. J Agric Res 50:135–147

    Google Scholar 

  • Raper K (1940) Pseudoplasmodium formation and organization in Dictyostelium discoideum. J Elisha Mitchell Sci Soc 56:241–287

    Google Scholar 

  • Ratner D, Borth W (1983) Comparison of differentiating Dictyostelium discoideum cell types separated by an improved method of density gradient centrifugation. Exp Cell Res 143:1–13

    Article  PubMed  CAS  Google Scholar 

  • Roos W, Scheidegger C, Gerisch G (1976) Adenylate cyclase activity oscillations as signals for cell aggregation in Dictyostelium discoideum. Nature 226:259–261

    Google Scholar 

  • Rubino S, Mann S, Hori R, Pinko C, Firtel R (1989) Molecular analysis of a developmentally regulated gene required for Dictyostelium aggregation. Dev Biol 131:27–36

    Article  PubMed  CAS  Google Scholar 

  • Sakai Y (1973) Cell type conversion in isolated prestalk and prespore fragments of the cellular slime mold Dictyostelium discoideum. Dev Growth Differ 15:11–19

    Article  Google Scholar 

  • Schindler J, Sussman M (1977) Ammonia determines the choice of morphogenetic pathways in Dictyostelium discoideum. J Mol Biol 116:161–170

    Article  PubMed  CAS  Google Scholar 

  • Shimkets L, Dworkin M (1981) Excreted adenosine is a cell density signal for the initiation of fruiting body formation in Myxococcus xanthus. Dev Biol 84:51–60

    Article  PubMed  CAS  Google Scholar 

  • Siu CH, Lerner R, Ma G, Firtel R, Loomis WF (1976) Developmentally regulated proteins of the plasma membrane of Dictyostelium discoideum. The carbohydrate-binding protein. J Mol Biol 100:157–178

    Article  PubMed  CAS  Google Scholar 

  • Spudich J (1987) Dictyostelium discoideum: molecular approaches to call biology. Methods Cell Biol 28:1–516

    Article  Google Scholar 

  • Sternberg P (1988) Lateral inhibition during vulval induction in Caenorhabditis elegans. Nature 335:551–554

    Article  PubMed  CAS  Google Scholar 

  • Sternfeld J, David CN (1982) Fate and regulation of anterior-like cells in Dictyostelium slugs. Dev Biol 93:111–118

    Article  PubMed  CAS  Google Scholar 

  • Sussman M (1987) Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions. Methods Cell Biol 28:9–29

    Article  PubMed  CAS  Google Scholar 

  • Sussman R, Sussman M (1953) Cellular differentiation in Dictyosteliaceae: heritable modifications of the developmental pattern. Ann NY Acad Sci 56:949–960

    Article  PubMed  CAS  Google Scholar 

  • Tasaka M, Takeuchi I (1981) Role of cell sorting in pattern formation in Dictyostelium discoideum. Differentiation 18:191–196

    Article  PubMed  CAS  Google Scholar 

  • Van Haastert P, van Lookern Campagne M, Roos F (1982) Altered cGMP-phosphodiesterase activity in chemotactic mutants of Dictyostelium discoideum. FEBS Lett 147:149–152

    Article  PubMed  Google Scholar 

  • Weijer CJ, Duschl G, David CN (1984) Dependence of cell-type proportioning and sorting on cell cycle phase in Dictyostelium discoideum. J Cell Sci 70:133–145

    PubMed  CAS  Google Scholar 

  • Wessels D, Soll DR, Knecht DA, Loomis WF, DeLozanne A, Spudich J (1988) Cell motility and chemotaxis in Dictyostelium amoebae lacking myosin heavy chain. Dev Biol 128:164–177

    Article  PubMed  CAS  Google Scholar 

  • West C, Lubniewski A, Gregg J, Newton B (1982) A temperature-dependent choice in cell differentiation. Differentiation 23:91–102

    Article  PubMed  CAS  Google Scholar 

  • Williams J (1988) The role of diffusible molecules in regulating the cellular differentiation of Dictyostelium discoideum. Development 103:1–16

    PubMed  CAS  Google Scholar 

  • Williams J, Pears C, Jermyn K, Driscoll D, Mahbubani H, Kay R (1986) The control of gene expression during cellular differentiation of Dictyostelium discoideum. In: Booth I, Higgins C (eds) Symp Soc Microbiol. Cambridge University Press, pp 277–298

    Google Scholar 

  • Williams J, Ceccarelli A, McRobbie S, Mahbubani H, Kay R, Berks A, Jermyn K (1987) Direct induction of Dictyostelium prestalk gene expression by DIF provides evidence that DIF is a morphogen. Cell 49:185–192

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Center for Molecular Genetics, University of California San Diego, LaJolla, CA, 92093, USA

    W. F. Loomis

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  1. W. F. Loomis
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Editors and Affiliations

  1. UA CNRS 1191, Laboratoire de Biologie Moléculaire, Université des Sciences et Technique du Languedoc, 34060, Montpellier Cedex, France

    Philippe Jeanteur

  2. Research Institute, National Cancer Center, Tsukiji 5-chome, Chuo-ku, Tokyo 104, Japan

    Yoshiyuki Kuchino

  3. Abt. Angewandte Molekularbiologie, Physiologisch-Chemisches Institut, Duesbergweg 6, 6500, Mainz, Germany

    Werner E. G. Müller

  4. Department of Biological Sciences, St. John’s University, Grand Central & Utopia Parkways, Jamaica, New York, 11439, USA

    Philip L. Paine

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Loomis, W.F. (1990). Essential Genes for Development ofDictyostelium . In: Jeanteur, P., Kuchino, Y., Müller, W.E.G., Paine, P.L. (eds) Progress in Molecular and Subcellular Biology. Progress in Molecular and Subcellular Biology, vol 11. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75178-3_7

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  • DOI: https://doi.org/10.1007/978-3-642-75178-3_7

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