Abstract
The concept that organic molecules may be regarded as collections of generally spherical atoms, connected to one another by rod-like bonds is well-established and has, for many years, provided the basis upon which chemists visualise structures, in either two or three dimensions. Fabrication of atoms and bonds from wood, metal or plastic has been done increasingly since 1950; an important property of such physical models is that they can be made to be dimensionally accurate. Thus the well-known Dreiding models [1], designed by André Dreiding are constructed from stainless steel and preserve bond lengths and bond angles, while reducing all atoms to points with zero atomic radius. The CPK models [2] on the other hand, generally built with a plastic material, have atoms of the correct radius and also preserve bond lengths and bond angles. Both of these, and other types of models are used commonly by chemists who are concerned with the overall shape of molecules, a property that is clearly important in determining their behaviour.
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Drieding models, designed by Drieding at the University of Zurich, as available from Fisher Scientific (Pittsburgh, PA).
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Milne, G.W.A., Driscoll, J.S., Marquez, V.E. (1989). Molecular modelling in drug design. In: Collier, H.R. (eds) Chemical Information. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75165-3_3
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DOI: https://doi.org/10.1007/978-3-642-75165-3_3
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