Timescale for Development of DNA Damage
During this thursday afternoon session the problems dealt with extended from the primary ionization events within the stacked bases of the DNA molecule itself, studied by multiphoton laser flash photolysis (Schulte-Frohlinde), through the very elegant measurements of the timescale for chemical repair using the gas explosion technique (Michael), to the effects of extracellular chemical agents on the eventual biological end-points (van der Schans, Held and Edgren). In an attempt to provide some cohesion between the talks and to be able to place the various aspects discussed in the general overal framework of cellular radiation damage a physical chemist’s schematic view of the biological machinery involved was provided by the chairman.
KeywordsRadical Site Pulse Radiolysis Radical Repair Laser Flash Photolysis Millisecond Timescale
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