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Models to Link DNA Damage to RBEs for Final Cellular Effects

  • Dudley T. Goodhead
Part of the NATO ASI Series book series (volume 54)

Abstract

A major aim of research on the biological effects of radiation is to understand and be able to model the chain of processes from the initial radiation insult to the final observable effects in mammalian cells. It is widely believed that for many cellular effects of interest damage to DNA is a critical element in this chain. We may wonder, then, how this acts as an intermediate step in determining the relative biological effectiveness (RBE) of different ionising radiations.

Keywords

Ionise Radiation Energy Deposition Relative Biological Effectiveness Track Structure Radiation Track 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Dudley T. Goodhead
    • 1
  1. 1.Medical Research Council Radiobiology UnitChilton Didcot ORDUK

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