Advertisement

What Basis for the Development of Radiation-Induced DNA Damage?

  • Hooshang Nikjoo
Part of the NATO ASI Series book series (volume 54)

Abstract

To account for the observed biological effects a multitude of different physical and chemical processes have been put forward todate. In terms of time domains molecular effects are referred to as ‘direct-effect’ (D) and ‘indirect-effect’ (ID). There exist a number of definitions for these terms: (D) effect due to ionisation or excitation of the DNA molecule, (D) effects not modified by radical scavenging species, (D) thermal excitation of DNA by internal conversion, (ID) damage caused by reactive species and (ID) damage due to finite migration of free radicals.

Keywords

Indirect Effect Reactive Species Energy Deposition Internal Conversion Thermal Excitation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Hooshang Nikjoo
    • 1
  1. 1.MRC Radiobiology UnitChilton, OxonUK

Personalised recommendations