Abstract
The first stages of direct damage from ionising radiation are the ionisation and excitation of atoms in the DNA molecule and the consequential production of single strand breaks (ssb). These, if on opposite strands and close together, can combine to produce double strand breaks (dsb). In turn it is likely that a small fraction of dsb combine to produce a variety of chromosome aberrations endangering cell reproduction.
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© 1991 Springer-Verlag Berlin Heidelberg
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Charlton, D.E. (1991). The Application of Biophysical Models to Cellular DNA Damage. In: Fielden, E.M., O’Neill, P. (eds) The Early Effects of Radiation on DNA. NATO ASI Series, vol 54. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75148-6_19
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DOI: https://doi.org/10.1007/978-3-642-75148-6_19
Publisher Name: Springer, Berlin, Heidelberg
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