Abstract
Chloroplast ribosomes have many structural and functional features in common with bacterial type ribosomes (70S) notably the sensitivity towards a wide range of antibiotic substances which interfere with one or several steps of protein synthesis. It is known for a long time that e.g. streptomycin (Sm) specifically blocks protein synthesis within chloroplasts without affecting the function of cytosolic ribosomes. Prolonged exposure to Sm leads, e.g., to irreversibly bleached Euglena gracilis cells lacking photosynthetically active chloroplasts. On the other hand several Sm-resistant or Sm-dependent mutants were described both for algae (Nicolas, 1981, Boschetti and Bogdanov, 1973, Bartlett et al., 1979) and higher plants (Maliga et al., 1975) and it was argued that such mutations occurred on the chloroplast genome, however, without characterization of the mutated loci on the nucleotide level.
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© 1991 Springer-Verlag Berlin Heidelberg
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Stutz, E., Bonny, C. (1991). Interaction of Streptomycin with 16s Rrna of Chloroplasts and E.Coli. In: Mache, R., Stutz, E., Subramanian, A.R. (eds) The Translational Apparatus of Photosynthetic Organelles. NATO ASI Series, vol 55. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75145-5_14
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DOI: https://doi.org/10.1007/978-3-642-75145-5_14
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