The mom Operon of Bacteriophage MU is Regulated by a Combination of Transcriptional and Translational Controls

  • F. G. Wulczyn
  • F. Schmidt
  • A. Seiler
  • R. Kahmann
Conference paper
Part of the NATO ASI Series book series (volume 49)


The mom operon of bacteriophage Mu has proven to be an attractive model system for the study of prokaryotic gene regulation. Of particular interest is the integration of transcriptional and post-transcriptional controls in the regulation of mom gene expression. mom regulation has been recently reviewed (Kahmann and Hattman, 1987), in this chapter we will focus on progress made in the last few years. Transcriptional regulation will be briefly discussed, followed by a more comprehensive treatment of post-transcriptional control. New data on the mRNA sites involved in post-transcriptional regulation will be presented, and the overexpression and purification of the regulatory Com protein will be described.


Fusion Plasmid Tris Hydrochloride GATC Site Phage Development Attractive Model System 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • F. G. Wulczyn
    • 1
  • F. Schmidt
    • 1
  • A. Seiler
    • 1
    • 2
  • R. Kahmann
    • 1
  1. 1.Institut für Genbiologische Forschung Berlin GmbHGermany
  2. 2.Max Planck Institut für molekülare GenetikGermany

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