Effects of the 5′-Leader Sequence of Tobacco Mosaic Virus RNA, or Derivatives Thereof, on Foreign mRNA and Native Viral Gene Expression

  • T. Michael
  • A. Wilson
  • Keith Saunders
  • Mandy J. Dowson-Day
  • David E. Sleat
  • Hans Trachsel
  • Karl W. Mundry
Conference paper
Part of the NATO ASI Series book series (volume 49)


The primary function of a viral genome is to replicate to produce progeny virions. To achieve this, the exquisitely compact genetic information must perform several functions very efficiently and it is not uncommon for one sequence to fulfil several unrelated tasks. One such pleiotropic sequence, the 5′-untranslated leader of tobacco mosaic virus (TMV) RNA, is the main subject of this article.


Tobacco Mosaic Virus Leader Sequence Cowpea Chlorotic Mottle Virus Codon Context mRNA Leader 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • T. Michael
    • 1
  • A. Wilson
    • 1
  • Keith Saunders
    • 1
    • 2
  • Mandy J. Dowson-Day
    • 1
    • 3
  • David E. Sleat
    • 1
    • 4
  • Hans Trachsel
    • 1
    • 5
  • Karl W. Mundry
    • 1
    • 6
  1. 1.Center for Agricultural Molecular BiologyRutgers UniversityNew BrunswickUSA
  2. 2.Department of Virus ResearchJohn Innes Institute, AFRC IPSRNorwichUK
  3. 3.Nitrogen Fixation Laboratory, AFRC IPSRSussex UniversityBrightonUK
  4. 4.Department of Plant PathologyCornell UniversityIthacaUSA
  5. 5.Institut fur Biochemie und MolekularbiologieUniversität BernBernSwitzerland
  6. 6.Biologisches InstitutUniversität StuttgartStuttgart 80Germany

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