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Overexpression of Protein Kinase C α in Swiss/3T3 Cells Reduces The Number of Both High and Low Affinity of the Epidermal Growth Factor Receptors

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Biological Signal Transduction

Part of the book series: NATO ASI Series ((ASIH,volume 52))

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Abstract

The signaling pathways induced by growth factors and hormones can be divided into two major classes according to the second messangers they produce. In one pathway activation of G-proteins and adenylate cyclase produces the second massenger cAMP, while in the other pathway a rapid turnover of phospholipids generates two second messangers IP3 and diacylglycerol (for review Berrdige, 1987).

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© 1991 Springer-Verlag Berlin Heidelberg

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Eldar-Finkelman, H., Zismann, Y., Ullrich, A., Livneh, E. (1991). Overexpression of Protein Kinase C α in Swiss/3T3 Cells Reduces The Number of Both High and Low Affinity of the Epidermal Growth Factor Receptors. In: Ross, E.M., Wirtz, K.W.A. (eds) Biological Signal Transduction. NATO ASI Series, vol 52. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-75136-3_19

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  • DOI: https://doi.org/10.1007/978-3-642-75136-3_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-75138-7

  • Online ISBN: 978-3-642-75136-3

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