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G Protein-Coupled Receptors: Structural Basis of Selective Signaling

  • Elliott M. Ross
Part of the NATO ASI Series book series (volume 52)

Abstract

Animal cells must respond appropriately to multiple hormonal signals. These signals, which may be mutually potentiative or antagonistic, must be integrated to yield appropriate intracellular signals in the form of second messengers, such as cyclic AMP, inositol phosphates, Ca2+, etc. Although receptors are responsible for detecting extracellular signals, signal integration and sorting frequently depend on the activities of GTP-binding transducer proteins known as G proteins.

Keywords

Adrenergic Receptor Intracellular Loop Cytoplasmic Loop Chimeric Receptor Wasp Venom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • Elliott M. Ross
    • 1
  1. 1.Department of Pharmacology Southwestern Graduate School of Biomedical ScienceUniversity of Texas Southwestern Medical CenterDallasUSA

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