Animated Pseudocolor Activity Maps (Pam’s): Scientific Visualization of Brain Electrical Activity

  • David M. Senseman
  • Sylvia Vasquez
  • Patrick L. Nash
Part of the NATO ASI Series book series (volume 39)


Major advances in neuroscience have often followed directly from the application of new and more powerful methodological approaches to the study of brain structure and function (Clarke & Jacyna, 1987). Within the last decade a new technique has been developed that allows both brain structure and function to be studied in a closely integrated and highly complimentary fashion. This technique is multiple-site optical recording of membrane potential, or more simply, optical recording. Optical recording is based upon the ability of certain vital dyes (potentiometric probes) to optically signal changes in intracellular membrane potential. By viewing brain tissue stained with a voltage-sensitive dye with a suitable light detector system, changes in neuronal activity can be monitored simultaneously from a 100 or more contiguous anatomical regions (cf. Grinvald et al., 1988).


Optical Signal Video Image Olfactory Nerve Optical Recording Graphic Workstation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • David M. Senseman
    • 1
  • Sylvia Vasquez
    • 1
  • Patrick L. Nash
    • 2
  1. 1.Brain Research Laboratory Division of Life SciencesThe University of Texas at San AntonioSan AntonioUSA
  2. 2.Division of Earth & Physical SciencesThe University of Texas at San AntonioSan AntonioUSA

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