In Vivo Experimental Approaches to Hypotheses Concerned with Regeneration in the Mammalian CNS

  • Dorothy Eve Oorschot
  • David Gareth Jones
Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 119)

Abstract

Hypotheses concerned with regeneration in the CNS have been studied using a number of in vivo experimental approaches. These include the comparison of regenerative events in mammalian and submammalian vertebrates, as well as the comparison of mammalian developmental and regenerative events. The regenerative response of mammals has also been assessed using a variety of morphological and biochemical techniques; these studies primarily describe events at the lesion site. Attempts have also been made to promote CNS regeneration, and among these the use of transplants or pharmacological treatment is particularly noteworthy. In this section an assessment is made of the data generated by these approaches, in relation to the hypotheses described in Sect. 1.

Keywords

Dopamine DMSO Corticosteroid Polysaccharide Polypeptide 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • Dorothy Eve Oorschot
    • 1
  • David Gareth Jones
    • 1
  1. 1.Department of AnatomyUniversity of Otago Medical SchoolDunedinNew Zealand

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