Temperature/Signal Relations of Thermoreceptors and Input/Output Relations of the Thermoregulatory System

  • C. Jessen
  • G. Kuhnen
Conference paper

Abstract

The relationship between skin temperature (TSKIN) and the static discharge rate of mammalian cold receptors bears a characteristic pattern: starting from a near-zero level of activity at 44°CTSKIN the discharge rate increases in a sigmoid-like curve to a maximum around 29°C, and decreases with further decreasing temperature (Hensel and Kenshalo 1969). When Benzinger (1969) determined the relationship between TSKIN and metabolic rate (MR in a single human subject, he obtained bell-shaped curves with maximum MR at around 20°C TSKIN and remarkably symmetrical flanks at either side of the peak. These experiments, however, most likely involved highly dynamic conditions of changing core and skin temperatures, which possibly complicated the relationship. A recently developed technique (Nagel et al. 1986) permits skin and core temperatures of conscious animals to be altered or to be kept constant at various levels independently of each other. We have used this method to re-examine the question whether the bellshaped pattern of the cold receptor signals is reflected in the relationship between Tskin and MR.

Keywords

Norepinephrine Epinephrine 

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References

  1. Benzinger TH (1969) Heat regulation: homeostasis of central temperature in man. Physiol Rev 49:671–759.PubMedGoogle Scholar
  2. Clarke RSJ, Hellon RF, Lind AR (1958) The duration of sustained contractions in the human forearm at different muscle temperatures. J Physiol 143:454–473.PubMedGoogle Scholar
  3. Davies SN (1983) Effects of sympathetic stimulation on the discharge of trigeminal thermoreceptive and mechanoreceptive cells in the rat. J Physiol 341:50.Google Scholar
  4. Davies SN (1984) Sympathetic stimulation causes a frequency-dependent excitation and suppression of thermoreceptive cells in the trigeminal nucleus of the rat. J Physiol 350:22.Google Scholar
  5. Davies SN, Goldsmith GE, Hellon RF, Mitchell D (1983) Facial sensitivity to rates of temperature change: neurophysiological and psychophysical evidence from cats and humans. J Physiol 344:161–175.PubMedGoogle Scholar
  6. Dubner R, Sumino R, Wood WJ (1975) A peripheral cold fiber population responsive to innocuous and noxious thermal stimuli applied to the monkey’s face. J Neurophysiol 38:1373–1389.PubMedGoogle Scholar
  7. Hensel H (1973) Neural processes in thermoregulation. Physiol Rev 53:948–1017.Google Scholar
  8. Hensel H, Kenshalo DR (1969) Warm receptors in the nasal region of cats. J Physiol (Lond) 204:99–112.Google Scholar
  9. Holmer I, Bergh U (1974) Metabolic and thermal response to swimming in water at various temperatures. J Appl Physiol 37:702–705.PubMedGoogle Scholar
  10. Kuhnen G, Jessen C (1988) The metabolic response to skin temperature. Pflügers Arch 412:402–408.PubMedCrossRefGoogle Scholar
  11. Molinari HH, Kenshalo DR (1977) Effect of cooling rate on the dynamic response of cat cold units. Exp Neurol 55:546–555.PubMedCrossRefGoogle Scholar
  12. Nagel A, Herold W, Roos U, Jessen C (1986) Skin and core temperatures as determinants of heat production and heat loss in the goat. Pflügers Arch 406:600–607.PubMedCrossRefGoogle Scholar
  13. Necker R, Bicher G (1979) Methods of analyzing dynamic responses of temperature-sensitive neurons. Experientia 35:1340–1342.PubMedCrossRefGoogle Scholar
  14. Petrofsky JS, Lind AR (1975) Insulative power of body fat on deep muscle temperatures and isometric endurance. J Appl Physiol 39:639–642.PubMedGoogle Scholar
  15. Roos U, Jessen C (1987) No dynamic effector responses to fast changes of core temperature at constant skin temperature. Can J Physiol Pharmacol 65:1339–1346.PubMedCrossRefGoogle Scholar
  16. Schaefer K (1984) Modification of cold fibre activity by epinephrine and norepinephrine. Pflügers Arch 400:R67.Google Scholar
  17. Simon E, Iriki M (1971) Sensory transmission of spinal heat and cold sensitivity in ascending spinal neurons. Pflügers Arch 328:103–120.PubMedCrossRefGoogle Scholar
  18. Wünnenberg W, Brück K (1970) Studies on the ascending pathways from the thermosensitive regions of the spinal cord. Pflügers Arch 321:233–241.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • C. Jessen
  • G. Kuhnen
    • 1
  1. 1.Physiologisches InstitutJustus-Liebig-UniversitätGießenGermany

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