Abstract
The relaxation rate of water in the presence of Gd-DTPA (gadolinium-diethylenetriamine pentaacetic acid), a contrast agent in magnetic resonance (MR) imaging, is determined by both the intrinsic relaxation rate of water and the relaxivity or relaxation rate contribution (RRC) of Gd-DTPA, as shown by the following equation (Gadian et al. 1985):
where 1/Tpost and 1/Tpre are either T1 or T2 relaxation of water with and without Gd-DTPA. Although this RRC includes complex physical factors, in living tissue it indicates the degree of tissue concentration of Gd-DTPA or its accessibility to tissue water.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Berry I, Brant-Zawadzki M, Osaki L, Brasch R, Murovic J, Newton TH (1986) Gd-DTPA in clinical MR of the brain. II. Extraaxial lesions and normal structures. AJNR 7:789–793
Carter LP, Beggs J, Waggener JD (1972) Ultrastructure of three choroid plexus papillomas. Cancer 30:1130–1136
Gadian DG, Payne JA, Bryant DJ, Young IR, Carr DH, Bydder GM (1985) Gadolinium-DTPA as a contrast agent in MR imaging - theoretical projections and practical observations. J Comput Assist Tomogr 9:242–251
Ham AW (1974) Connective tissue: how fluid passes in and out through capillary walls. In: Ham AW (ed) Histology, 7th edn. Lippincott, Philadelphia, pp 213–215
Hirano A, Dembitzer HM, Zimmerman HM (1972) Fenestrated blood vessels in neurilemoma. Lab Invest 27:305–309
Kasantikul V, Glick AD, Netsky MG (1979) Light and electron microscopic observations of blood vessels in neurilemoma. Arch Pathol Lab Med 103:683–687
Long DM (1973) Vascular ultrastructure in human meningiomas and schwannomas. J Neurosurg 38:409–419
Mikhael MA, Ciric IS, Wolff AP (1985) Differentiation of cerebellopontine angle neuromas and meningiomas with MR imaging. J Comput Assist Tomogr 9:852–856
Press GA, Hesselink JR (1988) MR imaging of cerebellopontine angle and internal auditory canal lesions at 1.5 T. AJNR 9:241–251
Ramsey HJ (1966) Fine structure of hemangiopericytoma and hemangioendothelioma. Cancer 19:2005–2018
Riederer SJ, Bobman SA, Lee JN, Farzaneh F, Wang HZ (1986) Improved precision in calculated T1 MR images using multiple spin-echo acquisition. J Comput Assist Tomogr 10:103–110
Schelin U (1962) Chromophobe and acidophil adenomas of the human pituitary gland. A light and electron microscopic study. Acta Pathol Microbiol Scand [Suppl] 158:5–80
Schmiedl U, Ogan M, Paajanen H, Marotti M, Crooks LE, Brito AC, Brasch RC (1987) Albumin labeled with Gd-DTPA as an intravascular, blood pool-enhancing agent for MR imaging: biodistribution and imaging studies. Radiology 162:205–210
Watabe T, Azuma T (1989) T1 and T2 measurement of meningiomas and neuromas before and after Gd-DTPA. AJNR 10:463–470
Weinmann H-J, Brasch RC, Press W-R, Wesbey GE (1984) Characteristics of gadolinium-DTPA complex: a potential NMR contrast agent. AJR 142:619–624
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Watabe, T., Iwata, T. (1990). Tissue Accessibility of Gd-DTPA in Meningiomas and Neuromas. In: Higer, H.P., Bielke, G. (eds) Tissue Characterization in MR Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74993-3_47
Download citation
DOI: https://doi.org/10.1007/978-3-642-74993-3_47
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-74995-7
Online ISBN: 978-3-642-74993-3
eBook Packages: Springer Book Archive