Abstract
Since 1984 more than 600 patients with suspected breast disease have undergone MRI at our department, including more than 400 examinations using Gd-DTPA. Besides MRI with Gd-DTPA, in the early days of MRI T1 and T2 measurements were considered to have potential as a means of tissue characterization. However, despite all efforts the diagnostic value of T1 and T2 measurements obtained from clinical in vivo imaging has been disappointing. Several reasons have been discussed, including inaccuracy of T1 and T2 determination when based on two measurements only, systematic errors caused by the slice or volume selection method of the imaging system, and possible overlap of tissue parameters of histologically different tissues due to biologically similar composition. Due to these restrictions it is not yet clear whether the calculation of T1, T2, and proton density is a possible means of tissue characterization. To obtain reliable results, it is necessary to use very precise methods for T1 and T2 quantification. This is a report about our experiences concerning the in vivo determination of T1 from multiple measurement points using a sequence scheme called TOMROP.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Reference
Look DC, Locker DR (1970) Timesaving in measurements of NMR and EPR relaxation times. Rev Sci Instrum 41:250–251
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Hilbertz, T., Heywang, S.H., Beck, R., Deimling, M. (1990). T1 Measurements by TOMROP: First Experiences and Applications in In Vivo Breast Studies. In: Higer, H.P., Bielke, G. (eds) Tissue Characterization in MR Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74993-3_41
Download citation
DOI: https://doi.org/10.1007/978-3-642-74993-3_41
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-74995-7
Online ISBN: 978-3-642-74993-3
eBook Packages: Springer Book Archive