Abstract
In magnetic resonance imaging (MRI), the signal intensity depends indirectly on particular physical and chemical characteristics of the tissues being imaged. These tissue properties influence the behavior of the nuclei undergoing resonance and their behavior is what directly affects the MRI signal. The parameters of interest that describe this behavior are the relaxation times Tl and T2, the spin density [for hydrogen, N(H)], and the microscopic (diffusion) and macroscopic (flow, motion) motional states of the nuclei. As has often been repeated, different imaging techniques result in different responses to these magnetic resonance (MR) parameters. Early speculation suggested that the MR parameters, in particular the relaxation times, would provide very specific diagnostic information on the state of tissue within the body. In fact the results in this area have been disappointing. While MRI has been extremely sensitive to disease within the body’s soft tissue, the specificity is much poorer. It is often difficult to make specific comments on the character of the lesion based on the MR data alone. Yet when properly used, the MR parameters can provide valuable information.
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References
Bobman SA, Riederer SJ, Lee JN, Suddarth SA, Wang HZ, MacFall JR (1985) Synthesized MR images: comparison with acquired images. Radiology 155:731
Cannon RL, Dave JV, Bezdek JC (1986) Efficient implementation of the fuzzy c-means clustering algorithms. IEEE Trans Pattern Anal Machine Intell 8:248
Davis P, Kaufman L, Crooks LE (1983) Tissue characterization. In: Margulis AR, Higgins C, Kaufman L, Crooks LE (eds) Clinical magnetic resonance imaging. University of California Press, San Francisco
Feinberg DA, Mills CM, Posin JP, Ortendahl DA, Hylton NM, Crooks LE, Watts JC et al. (1985) Multiple spin echo magnetic resonance imaging: technical concepts and clinical correlation. Radiology 155:437
Herfkens RF, Davis PL, Crooks LE et al. (1981) NMR imaging of the abnormal live rat and correlation with tissue characteristics. Radiology 141:211
Herfkens RJ, Sievers R, Kaufman L, Sheldon PE, Ortendahl DA, Lipton MJ, Crooks LE (1983) NMR imaging of infarcted muscle: a rat model. Radiology 147:761
Jungke M, von Seelen W, Bielke S, Meindl S, Grigat M, Pfannenstiel P (1988) A system for the diagnostic use of tissue characterizing parameters in NMR-tomography. In: de Graaf CN, Viergever MA (eds) Information processing in medical imaging. Plenum, New York, p 471
Kjos BO, Ehman RL, Brant-Zawadski M (1985a) Reproducibility of T1 and T2 relaxation times calculated from routine MR imaging sequences: phantom study. AJNR 6:277
Kjos BO, Ehman RL, Brant-Zawadski M, Kelley WK, Norman D, Newton TH (1985b) Reproducibility of relaxation times and spin density calculated from routine MR imaging sequences: clinical study of the CNS. AJNR 6:271
Koenig SH, Brown RD (1984) The importance of the motion of water in biomedical NMR. European Workshop on NMR in Medicine, Wiesbaden
Mills TC, Ortendahl DA, Hylton NM (1986) Investigation of partial flip angle magnetic resonance imaging. IEEE Trans Nucl Sci 33:496
Mills TC, Ortendahl DA, Hylton NM, Croosk LE, Carlson JW, Kaufman L (1987) Partial flip MRI. Radiology 162:531
Ortendahl DA, Carlson JW (1988) Segmentation of MRI images using fuzzy clustering. In: de Graaf CN, Viergever MA (eds) Information processing in medical imaging. Plenum, New York, p 91
Ortendahl DA, Hylton NM (1986) Tissue type identification by MRI using pyramidal segmentation and intrinsic parameters. In: Bacharach SL (ed) Information processing in medical imaging. Nijhoff, The Hague, p 62
Ortendahl DA, Hylton NM, Kaufman L, Crooks LE (1984a) Automated tissue characterization with NMR imaging. In: Deconinck F (ed) Information processing in medical imaging. Nijhoff, The Hague, p 477
Ortendahl DA, Hylton NM, Kaufman L, Watts J, Crooks LE, Mills CM, Stark D (1984b) Analytical tools for MRI. Radiology 153:479
Schmidley JW, Brito A, Chan PH et al. (1983) Using nuclear magnetic resonance (NMR) imaging to study changes in brain water (Abstr). Neurology (NY) 33:151
Winkler ML, Ortendahl DA, Mills TC, Crooks LE, Sheldon PE, Kaufman L, Kramer DM (1988) Characteristics of partial flip angle and gradient reversal MR imaging. Radiology 166:17
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© 1990 Springer-Verlag Berlin Heidelberg
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Ortendahl, D.A., Hylton, N.M., Kaufman, L. (1990). Tissue Characterization with MRI: The Value of the MR Parameters. In: Higer, H.P., Bielke, G. (eds) Tissue Characterization in MR Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74993-3_20
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DOI: https://doi.org/10.1007/978-3-642-74993-3_20
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