Abstract
Although the determination of tissue relaxation parameters from MRI intensities is straightforward in principle, a number of factors may render conventional analysis difficult in practice. Many of these nonideal factors have been studied theoretically and experimentally: effects of static and RF field in-homogeneities and RF phase imperfections on T2 measurements in pulse NMR experiments (Void et al. 1973), RF and static field inhomogeneity effects on T2 measurements derived from MRI multiecho images (Majumdar et al. 1986a, b), effects of selective pulses on T1 measurements (Joseph et al. 1984), analysis of multiexponential magnetization decay (Sandor et al. 1988), and “cross-talk” effects on T1 and T2 measurements in slice-selective MRI imaging experiments (Just et al. 1988).
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Armitage P (1980) Statistical methods in medical research. Blackwell, Oxford, pp 226–239
Hyman T, Kurland R, Levy G, Shoop J (1989) Characterization of normal brain tissue using seven calculated MRI parameters and a statistical analysis system. Magn Reson Med 11:22–34
Joseph P, Axel L, O‘Donnell L (1984) Potential problems with selective pulses in NMR. Med Phys 11:772–777
Just M, Higer H-P, Pfannenstiel P (1988) Errors in T1-determination using multislice technique and gaussian slice profiles. Magn Reson Imaging 6:53–56
Majumdar S, Orphanoudakis S-C, Gmitro A, O‘Donnell M, Gore J-C (1986a) Errors in the measurements of T2 using multiple-echo MRI techniques. I. Effects of radiofrequency pulse imperfections. Magn Reson Med 3:397–417
Majumdar S, Orphanoudakis S-C, Gmitro A, O‘Donnell M, Gore J-C (1986b) Errors in the measurements of T2 using multiple-echo MRI techniques. II. Effects of static field inhomogeneity. Magn Reson Med 3:562–574
Sandor T, Bleier A-R, Ruenzel P-W, Adams D-F, Jolesz F-A (1988) Application of the maximum likelihood principle to separate exponential terms in T2 relaxation of nuclear magnetic resonance. Magn Reson Imaging 6:27–40
Void R-L, Void R-R, Simon H-E (1973) Errors in measurements of transverse relaxation rates. J Magn Reson 11:283–298
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Shoop, J.D., Kurland, R.J., Hyman, T.J., Levy, G.C. (1990). MRI Relaxation of Brain Tissue: A Statistical Estimate of Deviations from Ideality. In: Higer, H.P., Bielke, G. (eds) Tissue Characterization in MR Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74993-3_14
Download citation
DOI: https://doi.org/10.1007/978-3-642-74993-3_14
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-74995-7
Online ISBN: 978-3-642-74993-3
eBook Packages: Springer Book Archive