Abstract
In the ageing laboratory rodents used for the testing safety of chemicals, toxicopathological effects which may occur, must be assessed against the background of natural ageing changes. The following issues are of particular concern: normal “age-related” data, consistency and relevance of pathology data, detection of subtle changes, age-related susceptibility to toxicants.
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© 1991 Springer-Verlag Berlin Heidelberg
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Krinke, G.J., Perrin, L.P.A., Hess, R. (1991). Assessment of Toxicopathological Effects in Ageing Laboratory Rodents. In: Chambers, P.L., Chambers, C.M., Wiezorek, W.D., Golbs, S. (eds) Recent Developments in Toxicology: Trends, Methods and Problems. Archives of Toxicology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74936-0_8
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DOI: https://doi.org/10.1007/978-3-642-74936-0_8
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-51422-0
Online ISBN: 978-3-642-74936-0
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