Abstract
The mechanism of the organophosphorous compounds, the inhibition of the enzyme cholinesterase causing a cholinergic crisis and special clinical signs of intoxication are well known (Hayes 1982, Klaassen et al 1986). The electrophysiological changes of the central and peripheral nervous system produced by these compounds have been investigated only by a few authors (Hyde et al 1978; Solima et al 1982; Dési 1983).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Dési I (1983) Neurological investigation of pesticides in animal experiments. Neurobehav Toxicol Teratol 5:503–515
Hayes WJ (1982) Toxicology of pesticides. Williams and Wilkins, Baltimore
Hyde KM, Crandall JC, Kortman KE, McCoy WK (1978) EEG, ECG and respiratory response to acute insecticide exposure. Bull Environm Contam Toxicol 19:47–55
Klaassen CD, Amdur MO, Doull J (1986) Toxicology. The basic science of poisons. Macmillan Publishing Company, New York
Nagymajtényi L, Dési I, Lorencz R (1988) Neurophysiological markers as early signs of organophosphate neurotoxicity. Neurotox Terat 10:429–434
Meinecke KH, Oettel H (1966) Mikromethode zur Bestimmung der Acetyl-cholinesteraseAktivität in Erythrozyten und Plasma von Mensch und Tier. Arch Toxicol 21:321–332
Solima SA, Farmer J, Curley A (1982) Is delayed neuropathy a property of all organophosphorous compounds? Toxicology 23:267–279
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Dési, I., Nagymajtényi, L., Lorencz, R., Molnár, Z. (1991). The Effects of Organophosphorous Compounds on the Central Nervous System of Rats. In: Chambers, P.L., Chambers, C.M., Wiezorek, W.D., Golbs, S. (eds) Recent Developments in Toxicology: Trends, Methods and Problems. Archives of Toxicology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74936-0_6
Download citation
DOI: https://doi.org/10.1007/978-3-642-74936-0_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-51422-0
Online ISBN: 978-3-642-74936-0
eBook Packages: Springer Book Archive