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Effects of Pyridinium,1-{[(4-Carbamoyl-Pyridinio) Methoxy] Methyl}-2-(Hydroxyimino-Methyl) Dichloride Monohydrate (HI6) and Atropine on the Circulation and Respiration of Anesthetized Guinea Pigs

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Recent Developments in Toxicology: Trends, Methods and Problems

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 14))

Abstract

Atropine (AT) and HI6 are effective antidotes in organophosphate (OP) poisoning. However, AT may enhance oxime-toxicity (Boskovic et al 1984), and a small overdose of HI6 may impair circulation seriously (Lipp and Dola 1980).

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References

  • Boskovic B, Kovacevic V, Jovanovic D (1984) PAM-2 Cl, HI-6, and HGG-12 in Soman and Tabun Poisoning. Fundam Appl Toxicol 4:S106–S115

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Author information

Authors and Affiliations

  1. Institut für Pharmakologie und Toxikologie, Akademie des Sanitäts- und Gesundheitswesens der Bundeswehr, Ingolstädter Landstraße 98, D-8046, Garching-Hochbrück, Germany

    S. De La Motte & L. Szinicz

Authors
  1. S. De La Motte
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  2. L. Szinicz
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Editor information

Editors and Affiliations

  1. Department of Pharmacology and Therapeutics, Trinity College, University of Dublin, Dublin 2, Ireland

    Philip L. Chambers  & Claire M. Chambers  & 

  2. Institut für Pharmakologie und Toxikologie, Universität Leipzig, Universitätsbereich Medizin, Härtelstraße 16-18, O-7010, Leipzig, Germany

    Wolf Diether Wiezorek

  3. Veterinärmedizinische Fakultät, Institut für Pharmakologie, Pharmazie und Toxikologie, Universität Leipzig, Zwickauer Straße 55, O-7010, Leipzig, Germany

    Siegfried Golbs

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© 1991 Springer-Verlag Berlin Heidelberg

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De La Motte, S., Szinicz, L. (1991). Effects of Pyridinium,1-{[(4-Carbamoyl-Pyridinio) Methoxy] Methyl}-2-(Hydroxyimino-Methyl) Dichloride Monohydrate (HI6) and Atropine on the Circulation and Respiration of Anesthetized Guinea Pigs. In: Chambers, P.L., Chambers, C.M., Wiezorek, W.D., Golbs, S. (eds) Recent Developments in Toxicology: Trends, Methods and Problems. Archives of Toxicology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74936-0_56

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  • DOI: https://doi.org/10.1007/978-3-642-74936-0_56

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51422-0

  • Online ISBN: 978-3-642-74936-0

  • eBook Packages: Springer Book Archive

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