Abstract
Among the volatile organic solvents, acetone (AC) 54% and ethyl acetate (EA) 39% were found as major components after toluene 69% in 101 glues analyzed in Germany (Auffarth and Häger 1989). Pulmonary absorption, biotransformation and excretion of acetone and ethyl acetate, as single solvents, have been thoroughly studied in man (Fernández and Droz 1974; Nomiyama and Nomiyama 1974; Wigaeus et al 1981). As there is no evidence available on combined exposures, studies of acute exposures to solvents of AC and EA in combination at Maximum Allowable Concentration (MAC) were carried out on humans in an exposure chamber to monitor the neurobehavioral effects, uptake and excretion during and after the exposure.
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References
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© 1991 Springer-Verlag Berlin Heidelberg
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Vangala, R.R., Blaszkewicz, M., Bolt, H.M., Golka, K., Kiesswetter, E., Seeber, A. (1991). Acute Experimental Exposures to Acetone and Ethyl Acetate. In: Chambers, P.L., Chambers, C.M., Wiezorek, W.D., Golbs, S. (eds) Recent Developments in Toxicology: Trends, Methods and Problems. Archives of Toxicology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74936-0_54
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DOI: https://doi.org/10.1007/978-3-642-74936-0_54
Publisher Name: Springer, Berlin, Heidelberg
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