Abstract
Glucose treatment improved the survival and symptomatology in mice poisoned with As2O3. In these experiments, irrespective of the treatment, the dying animals exhibited an almost complete depletion of glycogen in the liver (Reichl et al 1990). In order to obtain more insight into the mechanisms involved, postmortem changes of glucose and glycogen content in brain and muscle were investigated in animals acutely poisoned with As2O3 and treated with glucose or saline.
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© 1991 Springer-Verlag Berlin Heidelberg
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Reichl, F.X., Kreppel, H., Szinicz, L., Fichtl, B., Forth, W. (1991). Reduction of Arsenic Trioxide Toxicity in Mice by Repeated Treatment with Glucose. In: Chambers, P.L., Chambers, C.M., Wiezorek, W.D., Golbs, S. (eds) Recent Developments in Toxicology: Trends, Methods and Problems. Archives of Toxicology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74936-0_46
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DOI: https://doi.org/10.1007/978-3-642-74936-0_46
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