Mortality and Neoplastic Lesions in Untreated Sprague-Dawley Rats

  • J. Kaspareit-Rittinghausen
  • F. Deerberg
Part of the Archives of Toxicology book series (TOXICOLOGY, volume 14)


Data on tumour types and frequencies of rodent species obtained from longevity studies can be helpful tools for the interpretation of carcinogenicity studies, since conclusions concerning carcinogenicity of a particular substance require the knowledge of incidences of naturally occuring neoplasms of the animals under study. In the present paper a report is given on the mortality and the most important neoplastic lesions of untreated Han: SPRD rats kept in a life-span study from weaning to their natural death.


Mammary Gland Follicular Adenoma Spontaneous Tumour Mammary Gland Tumour Preputial Gland 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1991

Authors and Affiliations

  • J. Kaspareit-Rittinghausen
    • 1
  • F. Deerberg
    • 2
  1. 1.Squibb-von Heyden, Abt. ToxikologieRegensburg 13Germany
  2. 2.Central Institute for Laboratory Animal BreedingHannoverGermany

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