Abstract
Calcium antagonists are generally judged to be well tolerated drugs. Although, depending on substance and dosage, between 5% and 50% of all patients experience side effects (Table 31), the latter are frequently only minor and recede during the course of treatment. Severe side effects which lead to discontinuation of calcium antagonist therapy are relatively rare, the incidence stated in the literature lying between 1% and 5%, depending on the substance employed (Bleifeld and Spokojny 1983; Bussmann and Hopf 1985; see also Table 31). Thus, calcium antagonists can be considered, like β-receptor blockers, well-tolerated drugs (review by Lydtin and Lohmöller 1980), which is of particular significance since these drugs are often employed in long-term treatment, e.g. in stable angina pectoris or arterial hypertension.
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Lydtin, H., Trenkwalder, P. (1990). Side Effects — Overdosage — Contraindications — Drug Interactions. In: Calcium Antagonists. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74887-5_5
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