Interactions of 1α,25-Dihydroxyvitamin D3 and Hematopoietic Cells
The biologically active metabolite of vitamin D3, 1α,25-dihydroxyvitamin D3 [1α,25(OH)2D3], is recognized as a major hormonal regulator of calcium metabolism in man (Norman et al. 1982), Recently, evidence has been obtained for a wider biological role of 1α,25(OH)2D3 in tissues not primarily related to mineral metabolism. A prime example is the hematopoietic system, where new data indicate that 1α,25(OH)2D3 may influence the function of myeloid and lymphoid cells.
KeywordsLeukemia Cortisol Tuberculosis Testosterone Estradiol
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