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Isotope Effects in NMR Spectroscopy pp 31–80Cite as

Isotope Effects on Spin-Spin Coupling Constants: Experimental Evidence

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Part of the book series: NMR Basic Principles and Progress ((NMR,volume 22))

Abstract

The term “isotope effect” in NMR spectroscopy refers to changes of NMR spectral parameters that may arise due to isotopic substitution (mX/nX) of element X. Molecules AmX and AnX, differing in isotopes of element X, with A being an invariable part of the molecules are called isotopomers. Thus, isotope effects may be defined as:

$$ \Delta = \theta \left({{A^n}X} \right) - \theta \left({{A^m}X} \right)\,\left({n>m} \right) $$
(1)

where θ is the measured spectral characteristics.

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  1. NMR Laboratory, Department of Chemistry, Moscow State University, 119899, Moscow, USSR

    N. M. Sergeyev

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Sergeyev, N.M. (1990). Isotope Effects on Spin-Spin Coupling Constants: Experimental Evidence. In: Isotope Effects in NMR Spectroscopy. NMR Basic Principles and Progress, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74835-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-74835-6_2

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