Teilum (1959) first drew attention to the histological features of a tumour originally described by Schiller in 1939 as mesonephroma, which had a close structural resemblance to the rat placenta. He thought this structural display was an attempt at extra-embryonic differentiation; the tumour was therefore of germ cell origin. He designated the tumour as an endodermal sinus tumour.
KeywordsGerm Cell Tumour Endodermal Sinus Tumor Radical Vulvectomy Gonadal Tumour Fibrous Septae
Unable to display preview. Download preview PDF.
- Dudley AG, Young RH, Lawrence WD et al. (1983) Endodermal sinus tumor of the vulva in an infant. Obstet Gynecol 61 [Suppl]:76–79Google Scholar
- Gerhenson DM, Junco GD, Herson J et al. (1983) Endodermal sinus tumor of the ovary. Obstet Gynecol 61:194–202Google Scholar
- Huntington RH Jr, Bullock WK (1971) Endodermal sinus and other yolk sac tumours, a re-apprisal. Acta Pathol Microbiol Scand [A] 80 [Suppl 233]:26–31Google Scholar
- Nogales FF, Silverberg SG, Blaustein PA et al. (1977) Yolk sac carcinoma (endodermal sinus tumor): ultrastructural and histogenesis of gonadal and extragonadal tumors in comparison with normal human yolk sac. Cancer 39:1452–1472Google Scholar
- Schiller W (1939) Mesonephroma ovarii. Am J Cancer 35:1–21Google Scholar