Prophylactic and Adjuvant Regional Chemotherapy of the Liver in Colorectal Malignancies

  • H. H. Gruenagel
  • E. Molzahn
  • S. Neumann
  • G.-U. Neukamp
Conference paper

Abstract

The concept of prophylactic and adjuvant regional chemotherapy of the liver in colorectal malignancies is based on the fact that 25%–30% of the patients already have linear metastases at the time of primary resection. Of those without metastases at this time, 40%–50% develop liver metastases secondarily [2,8]. In view of this, Taylor perfused the liver via the recanalized umbilical vein with 1 g 5-fiuorouracil (5-FU) per day continuously for 7 days, starting immediately after curative resection of the tumor. He observed fewer liver metastases and better survival in the perfusion group [11].

Keywords

Catheter Adenocarcinoma Rubber Gall Bilirubin 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • H. H. Gruenagel
    • 1
  • E. Molzahn
    • 1
  • S. Neumann
    • 1
  • G.-U. Neukamp
    • 1
  1. 1.Chirurgische AbteilungEvangelisches Krankenhaus DüsseldorfDüsseldorf 1Germany

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