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Immunologische Untersuchungen zur Ursache des habituellen Abortes

  • O. Heine
  • J. Neppert
  • G. Mueller-Eckhardt
Conference paper

Summary

Female CBA/J (H-2k) mice mated with male DBA/2J (H-2d) mice show a high level of fetal resorption which can be reduced by immunization with BALB/c (H-2d) spleen cells. The morphologically defined fetal resorption rate upon which evaluation of the outcome of pregnancy has been based in this strain combination recently, is not equivalent to the rate of viable neonates.

Literatur

  1. 1.
    Chaouat G, Kiger N, Wegmann TG (1983) Vaccination against spontaneous abortion in mice. J Reprod Immunol 5: 389–392PubMedCrossRefGoogle Scholar
  2. 2.
    Kiger N, Chaouat G, Kolb JP, Wegmann TG, Guenet JL (1985) Immunogenetic studies of spontaneous abortion in mice. Preimmunization of females with allogeneic cells. J Immunol 134: 2966–2970Google Scholar
  3. 3.
    Mclntyre J, McConnachie PR, Taylor CG (1984) Clinical, immunological and genetical definitions of primary and secondary recurrent spontaneous abortions. Fertil Steril 42: 849–856Google Scholar
  4. 4.
    Mclntyre J, Faulk WP, Nichols-Johnson VR, Taylor CG (1986) Immunologic testing and immunotherapy in recurrent spontaneous abortion. Obstet Gynecol 67: 169–175CrossRefGoogle Scholar
  5. 5.
    Taylor C, Faulk WP (1981) Prevention of recurrent abortions with leucocyte transfusions. Lancet ii: 68–69Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • O. Heine
    • 1
  • J. Neppert
    • 2
  • G. Mueller-Eckhardt
    • 2
  1. 1.FrauenklinikUniversitäts-klinikumGießenDeutschland
  2. 2.Institut für Klinische Immunologie und TransfusionsmedizinUniversitäts-klinikumGießenDeutschland

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