Antihormone in der Gynäkologie

  • M. Breckwoldt
Conference paper

Zusammenfassung

Antihormone im engeren Sinne sind Substanzen, die mit einem Hormon um den spezifischen Rezeptor konkurrieren und damit die Hormonwirkung teilweise oder vollständig inhibieren. Hierher gehören Anti-Östrogene, Anti-Androgene und Anti-Gestagene. Die Wirkungsweise dieser Substanzen wird dargestellt, die Indikationen zu ihrer therapeutischen Anwendung werden erläutert. Ausführlich wird die ovulationsinduzierende Wirkung von Anti-Östrogenen besprochen. Zu den Antihormonen im weiteren Sinne gehören Substanzen wie Gn-RH-Agonisten, Gn-RH-Antagonisten und Dopamin-Agonisten. Auch für diese Substanzen werden Wirkungsweise und Anwendungsbereiche erläutert.

Summary

The therapeutic use of antihormones plays a significant and increasing role in gynecological practice. Antihormones in their true sense such as antiestrogens, antiandrogens, and antigestagens are defined as compounds competing with a given hormone at the receptor level of the target organ. Antihormones in a broader sense are compounds such as Gn-RH agonists, Gn-RH antagonists, and dopaminagonists. The mode of action of these compounds and the indication for their clinical application are outlined.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • M. Breckwoldt
    • 1
  1. 1.Universitäts-FrauenklinikFreiburg/BreisgauDeutschland

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