Skip to main content

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 94 / 1))

Abstract

There are many ways by which to define “environmental” carcinogens. Here the epithet “environmental” is taken to cover any unwanted, environmentally derived chemicals that enter the human body via food, drink or air and that have been shown to cause, or are suspected of causing, cancer in humans and/or experimental animals. As a further qualification, only man-made materials will be considered, with the exception of radon. The definition includes environmental contaminants in food but excludes food additives and natural ingredients. Mytotoxins, passive smoking and occupational carcinogens will not be dealt with because they are discussed elsewhere in this book. Furthermore, the effects of chlorofluorocarbons on stratospheric ozone levels, and thus indirectly on ultraviolet radiation and skin cancer, are beyond the scope of this chapter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Anderson EL (1985) Quantitative approaches in use in the United States to assess cancer risk. In: Youk VB, Butler GC, Hoel DG, Peakall DP (eds) Methods for estimating risk of chemical injury: human and non-human biota and ecosystems. SCOPE 26. Wiley, New York, pp 405–436.

    Google Scholar 

  • Anderson EL and the Carcinogen Assessment Group of the U.S. Environmental Protection Agency (1983) Quantitative approaches in use to assess cancer risk. Risk Analysis 3: 277–295.

    Google Scholar 

  • Castren O, Youtilainen A, Winquist K, Makelainen I (1985) Studies of high indoor radon areas in Finland. Sci Total Environ 45: 311–318.

    Article  PubMed  CAS  Google Scholar 

  • Czuczwa JM, Hites RA (1985) Dioxins and dibenzofurans in air, soil and water. In: Kamrin MA, Rodgers PW (eds) Dioxins in the environment. Hemisphere, Washington D.C.,pp 85–99

    Google Scholar 

  • Doll R, Peto R (1981) The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. JNCI66: 1191–1308.

    Google Scholar 

  • Gold LS (1980) Human exposures to ethylene dichloride. Banbury Rep 5: 209–225.

    Google Scholar 

  • Gold LS, Sawyer CB, Magaw R, Backman GM, De Veciana M, Levison R, Hooper NK, Havender WR, Bernstein L, Peto R, Pike MC, Ames BN (1984) A carcinogenic potency data base of the standardized results of animal bioassays. Environ Health Perspect 58: 9–319.

    Article  PubMed  CAS  Google Scholar 

  • Hemminki K, Vainio H (1984) Human exposure to potentially carcinogenic compounds. In: Berlin A, Draper M, Hemminki K, Vainio H (eds) Monitoring human exposure to carcinogenic and mutagenic agents. I ARC scientific publications No. 59. International Agency for Research on Cancer. Lyon, pp 37–45.

    Google Scholar 

  • Hemminki K, Vainio H, Sorsa M, Salminen S (1983) An estimation of the exposure of the population in Finland to suspected chemical carcinogens. Environ Carcinog Rev CI: 55–95.

    Google Scholar 

  • Hutzinger O, Choudry GG, Brock GC, Johnston LE (1985 a) Formation of polychlorinated dibenzofurans and dioxins during combustion, electrical equipment fires and PCB incineration. Environ Health Perspect 60: 3–9.

    Google Scholar 

  • Hutzinger O, Berg MVD, Olie K, Opperhuizen A, Safe S ( 1985 b) Dioxins and furans in the environment: evaluating toxicological risk from different sources by multi-criteria analysis. In: Kamrin MA, Rodgers PW (eds) Dioxins in the environment. Hemisphere, Washington D.C., pp 9–32.

    Google Scholar 

  • IARC (1979 a) I ARC monographs in the evaluation of the carcinogenic risk of chemicals to humans, vol 20. Some halogenated hydrocarbons. International Agency for Research on Cancer, Lyon I ARC (1979 b).

    Google Scholar 

  • IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, vol 19. Some monomers, plastics and synthetic elastomers, and acrolein. International Agency for Research on Cancer, Lyon I ARC (1982 a).

    Google Scholar 

  • IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, vol 29. Some industrial chemicals and dyestuffs. International Agency for Research on Cancer, Lyon I ARC (1982 b).

    Google Scholar 

  • IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, vol 29, supplement 4. Chemicals, industrial processes and industries associated with cancer in humans. International Agency for Research on Cancer, Lyon IARC (1984).

    Google Scholar 

  • IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, vol 34. Polynuclear aromatic compounds, part 3. Industrial exposures in aluminum production, coal gasification, coke production, and iron and steel founding. International Agency for Research on Cancer, Lyon IARC (1986)

    Google Scholar 

  • IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, vol 38. Tobacco smoking. International Agency for Research on Cancer, Lyon IARC (1987).

    Google Scholar 

  • IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, suppl 7. International Agency for Research on Cancer, Lyon Mossman KL, Thomas DS, Dritschilo A (1986) Environmental radiation and cancer. Environ Carcinog Rev C4(2):l 19–161.

    Google Scholar 

  • Rosenkranz HS, Mermelstein R (1985) The genotoxicity, metabolism and carcinogenicity of nitrated polycyclic aromatic hydrocarbons. J Environ Sci Health 3G221–272.

    Google Scholar 

  • Safe S, Bandiera S, Sawyer T, Robertson L, Safe L, Parkinson A, Thomas PE, Ryan DE, Reik LM, Levin W, Denomme MA, Fujita T (1985) PCBs: structure-function relationships and mechanism of action. Environ Health Perspect 60: 47–56.

    Google Scholar 

  • Slorach SA, Vaz R (1985) PCB levels in breast milk: data from the UNCP/WHO pilot project on biological monitoring and some other recent studies. Environ Health Perspect 60: 121–126.

    Article  PubMed  CAS  Google Scholar 

  • U.S. EPA (1979) Chlorinated ethanes. Ambient water quality criteria (draft). Criteria and Standards Division, Office of Water Planning and Standards, EPA, Washington D.C.

    Google Scholar 

  • U.S. EPA (1980) Guidelines and methodology used in the preparation of health effects assessment chapters of the consent decree water quality criteria. Fed Reg 45: 79347–79357.

    Google Scholar 

  • U.S. EPA (1981) Updated mutagenicity and carcinogenicity assessment of cadmium. Appendum to the health assessment document for cadmium. EPA/600/8–81/23. EPa/6/8–83/25F. June 1985. Final report. EPA, Washington D.C.

    Google Scholar 

  • U.S. EPA (1983) Health assessment document for acrylonitrile. Final report. EPA-600/8–82. Office of Health and Environmental Assessment, Washington D.C.

    Google Scholar 

  • U.S. EPA ( 1984 a) Health assessment document for inorganic arsenic. Final report. EPA-600/8–83–021F. Office of Health and Environmental Assessment, Washington D.C.

    Google Scholar 

  • U.S. EPA (1984b) Health assessment document for chromium. Final report. EPA-600/8–83 Environmental Criteria and Assessment Office, Research Triangle Park, North Carolina

    Google Scholar 

  • U.S. EPA (1985) Health assessment document for nickel. Final report. EPA-600/8–83/021F. Office of Health and Environmental Assessment, Washington D.C.

    Google Scholar 

  • UNSCEAR report to the general assembly with annexes (1982) Ionizing radiation: sources and biological effects. United Nations, New York Velema JP (1987) Contaminated drinking water as a potential cause of cancer in humans. Environ Carcinog Rev C5:l–28.

    Google Scholar 

  • WHO (1981) Environmental health criteria 18. Arsenic. World Health Organization, IPCS, Geneva

    Google Scholar 

  • WHO (1983 a) Environmental health criteria 27. Guidelines on studies in environmental epidemiology.

    Google Scholar 

  • World Health Organization, Geneva WHO (1983 b) Environmental health criteria 26. Styrene.

    Google Scholar 

  • World Health Organization, Geneva, p 123

    Google Scholar 

  • WHO (1984a) Guidelines for drinking-water quality, voll. Recommendations. World Health Organization, Geneva, p 130.

    Google Scholar 

  • WHO (1984b) Environmental health criteria 32. Methylene chloride. World Health Organization, Geneva, p 55.

    Google Scholar 

  • WHO ( 1984 c) Environmental health criteria 31. Tetrachloroethylene. World Health Organization, Geneva, p 48.

    Google Scholar 

  • WHO ( 1987 a) Air quality guidelines, vol 1–2. World Health Organization, Copenhagen.

    Google Scholar 

  • WHO ( 1987 b) Environmental health criteria 62. 1,2-Dichloroethane. World Health Organization, Geneva, p 90

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Hemminki, K. (1990). Environmental Carcinogens. In: Cooper, C.S., Grover, P.L. (eds) Chemical Carcinogenesis and Mutagenesis I. Handbook of Experimental Pharmacology, vol 94 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74775-5_2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-74775-5_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74777-9

  • Online ISBN: 978-3-642-74775-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics