Optimised Treatment Modalities for Hypoxic Tumour Cells

  • P. Workman
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)

Abstract

Solid tumours are made up of many different cell types, including heterogeneous neoplastic subpopulations. The targeting of therapeutic strategies to particular cell populations within tumours has therefore a sound rational basis. Considerable evidence supports the existence of hypoxic cells in solid tumours, and their role in limiting response to radiotherapy and chemotherapy [1,2].

Keywords

Glutathione Adduct Sarcoma Melphalan Thiol 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • P. Workman
    • 1
  1. 1.MRC Clinical Oncology and Radiotherapeutics UnitMRC CentreCambridgeUK

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