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Flow Cytometry in the Quantitation of DNA Aneuploidy and Cell Proliferation in Human Disease

  • Chapter
Pathology of the Nucleus

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 82))

Abstract

The use of the technique of flow cytometry has rapidly expanded in the last 5 years and in certain areas such as immunology and the pharmaceutical industry flow cytometers are routine instruments. Concomitant with this expansion there has been an explosion in the volume of the literature, especially within the cancer journals. In this chapter the principles of flow cytometry will be explained, its present and future applications reviewed and examples of new techniques which may be of diagnostic and prognostic importance introduced. There are several reviews on this subject (Barlogie et al. 1983; Friedlander et al. 1984 a; Quirke and Dyson 1986; Ryan et al. 1988) along with a few books (Melamed et al. 1979; Shapiro 1985) from which further information can be obtained.

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Authors
  1. P. Quirke
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Editors and Affiliations

  1. Department of Pathology, University of Sheffield Medical School, Beech Hill Road, S10 2RX, Sheffield, UK

    James C. E. Underwood Professor, M.D., F.R.C. Path.

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© 1990 Springer-Verlag Berlin Heidelberg

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Quirke, P. (1990). Flow Cytometry in the Quantitation of DNA Aneuploidy and Cell Proliferation in Human Disease. In: Underwood, J.C.E. (eds) Pathology of the Nucleus. Current Topics in Pathology, vol 82. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74668-0_5

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  • DOI: https://doi.org/10.1007/978-3-642-74668-0_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-74670-3

  • Online ISBN: 978-3-642-74668-0

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