Treatment of Relapsed Acute Lymphocytic Leukemia in Adults

  • M. Freund
  • M. De Boben
  • H. Diedrich
  • A. Ganser
  • G. Heil
  • A. Heyll
  • M. Henke
  • W. Hiddemann
  • U. Knauf
  • P. Koch
  • M. Körbling
  • R. Küchler
  • H. Link
  • G. Maschmeyer
  • M. Planker
  • D. Renner
  • C. Schadeck-Gressel
  • N. Schmitz
  • U. von Verschuer
  • S. Wilhelm
  • D. Hoelzer
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 33)

Abstract

The treatment of acute lymphoblastic leukemia (ALL) with modern multidrug schedules is highly effective. In the first German multicenter study, 01/81, complete remissions were induced in 272 of 368 patients (73.9%), and in the second trial, 02/84, in 350 of 442 (79.2%) [1]. Though 35% of the patients remain disease free after 7.5 years in the first study and 48% after 3 years in the second, relapses are still frequent.

Keywords

Leukemia Oncol Diarrhea Methotrexate Prednisone 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • M. Freund
    • 1
    • 14
  • M. De Boben
    • 2
    • 14
  • H. Diedrich
    • 1
    • 14
  • A. Ganser
    • 3
    • 14
  • G. Heil
    • 4
    • 14
  • A. Heyll
    • 5
    • 14
  • M. Henke
    • 6
    • 14
  • W. Hiddemann
    • 7
    • 14
  • U. Knauf
    • 2
    • 14
  • P. Koch
    • 7
    • 14
  • M. Körbling
    • 2
    • 14
  • R. Küchler
    • 8
    • 14
  • H. Link
    • 1
    • 14
  • G. Maschmeyer
    • 9
    • 14
  • M. Planker
    • 10
    • 14
  • D. Renner
    • 11
    • 14
  • C. Schadeck-Gressel
    • 12
    • 14
  • N. Schmitz
    • 13
    • 14
  • U. von Verschuer
    • 9
    • 14
  • S. Wilhelm
    • 13
    • 14
  • D. Hoelzer
    • 3
    • 14
  1. 1.Dept. of Hematology/OncologyMedical SchoolHannoverGermany
  2. 2.Dept. of Internal Medicine-PoliklinikUniversity, HeidelbergGermany
  3. 3.Dept. of Internal Medicine, HematologyUniversity, FrankfurtGermany
  4. 4.Dept. of Internal Medicine IIIUniversity, UlmGermany
  5. 5.Dept. of Internal Medicine, Hematology/OncologyUniversity, DüsseldorfGermany
  6. 6.Dept. of Internal MedicineFreiburgGermany
  7. 7.Dept. of Internal Medicine, Hematology/OncologyUniversity, MünsterGermany
  8. 8.Dept. of HematologyAllgemeines Krankenhaus St. GeorgHamburgGermany
  9. 9.Dept. of Internal MedicineEvangelisches Krankenhaus Essen-WerdenGermany
  10. 10.Dept. of Internal Medicine IIStädtische Krankenanstalten KrefeldGermany
  11. 11.University Oncology CenterMannheimGermany
  12. 12.Dept. of Internal Medicine IISt. Johannes-Hospital DuisburgGermany
  13. 13.II. Dept. of Internal MedicineKielGermany
  14. 14.Section of Hematology/OncologyDept. of Internal Medicine IIKarlsruheGermany

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