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Therapy of Childhood Acute Myelogenous Leukemia: An Update of the AIEOP/LAM 8204 Study

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Abstract

Over the past decade there have been significant advances in the treatment of acute myelogenous leukemia (AML). The introduction of intensive induction and post-remission chemotherapy programs, together with the improvement in supportive care, have resulted in a probability of long-term survival in 30%–50% of children with AML [1–4]. In 1982 the AIEOP (Italian Pediatric Hematology-Oncology Association) cooperative group began a multicenter prospective trial for pediatric AML in order to establish the value of a polychemotherapeutic regimen consisting of intensive induction followed by intensive consolidation and continuation chemotherapy.

Supported by Consiglio Nazionale Ricerche (CNR), Progetto Finalizzato Oncologia (PFO) contract no. 87.02801.44 and by Ministero Pubblica Istruzione (MPI) 40%.

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References

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© 1990 Springer-Verlag Berlin Heidelberg

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Amadori, S. et al. (1990). Therapy of Childhood Acute Myelogenous Leukemia: An Update of the AIEOP/LAM 8204 Study. In: Büchner, T., Schellong, G., Hiddemann, W., Ritter, J. (eds) Acute Leukemias II. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 33. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-74643-7_40

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  • DOI: https://doi.org/10.1007/978-3-642-74643-7_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-50984-4

  • Online ISBN: 978-3-642-74643-7

  • eBook Packages: Springer Book Archive

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